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治疗麻风病的药物及其抗菌活性和毒副作用 被引量:4

Drug treatment of leprosy and its antibacterial activity and toxicity
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摘要 目的研究对麻风病进行治疗的药物,以及每种药物的抗菌活性和毒副作用。方法我院选择2012年8月至2013年8月间诊治的60例麻风病患者,对其运用药物实施治疗,观察药物的抗菌活性以及产生的毒副作用。结果通过观察可以发现,降低患者畸形和残疾的有效方法即为早期诊断和早期治疗,所应用的药物主要有氨苯砜(DDS)是治疗麻风的首选药物,其次还可以应用利福平(RFP)、氯苯吩嗪(B663)、氧氟沙星(OFLO)、米诺环素(MINO)、克拉霉素(CLARI)等等。大多数药物会导致患者出现消化道不良反应,如恶心、呕吐等症状。结论麻风性畸残是一个重要的医学和社会问题,因人们对麻风病充满着恐惧以及高度歧视麻风病患者,导致患者就医延迟,作为一名医务工作者,应掌握麻风病的各项数据,为这类患者争取资金,使其能够重新回到正常的学习、工作和生活中,降低患者及其家庭的经济压力,同时缓解整个社会的负担。 Objective To study the treatment of leprosy drugs,as well as antibacterial activity and side effects of each drug. Methods The hospital chose 60 cases of leprosy diagnosis and treatment between August2012 and August 2013,the use of the drug for its implementation of treatment,observation and antimicrobial activity of the drug's toxic side effects. Results Through observation found in patients with deformities,it was an effective way to reduce the disability in early diagnosis and early treatment,the drug was applied mainly daps one( DDS) was the drug of choice for treatment of leprosy,followed by rifampicin applied( RFP),clofazimine( B663),offloading( OFLO),minocycline( MINO),clarithromycin( CLARI),and so on. Most drugs caused adverse reactions in patients with gastrointestinal,such as nausea,vomiting and other symptoms. Conclusions Leprosy deformities is an important medical and social problem,because people are full of fear and leprosy height discrimination,leading to delay in medical treatment of patients as a medical work which should be mastered various data leprosy,to seek funding for these patients,so that it can return to normal learning,work and life,reduce the economic pressure of patients and their families,and to ease the burden on society as a whole.
出处 《齐齐哈尔医学院学报》 2015年第28期4244-4245,共2页 Journal of Qiqihar Medical University
关键词 麻风病 药物治疗 抗菌活性 毒副作用 Leprosy Drug therapy Antibacterial activity Side effect
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