摘要
目的探讨哌拉西林舒巴坦联合左氧氟沙星治疗老年肺炎患者的临床效果。方法选取我院2012年9月至2014年12月呼吸内科99例老年肺炎患者进行药物治疗效果研究,采取不同的药物治疗方案将患者随机分为三组,研究组患者采取哌拉西林舒巴坦联合左氧氟沙星治疗,对照组1所有患者均应用哌拉西林舒巴坦治疗,对照组2采取左氧氟沙星治疗,观察对比三组患者疗效与不良反应率。结果患者经治疗后,研究组治疗总有效率为96.97%,对照组1为72.73%,对照组2为75.76%,研究组总有效率明显高于对照组1与2,两组数据差异具有统计学意义(P<0.05);研究组总不良反应率为6.06%,对照组1为3.03%,对照组2为3.03%,研究组总不良反应率与对照组1与2相近,P>0.05,无统计学差异;对照组1与2总有效率与总不良反应率对比,P>0.05,无统计学差异。结论研究结果显示老年肺炎患者采取哌拉西林舒巴坦联合左氧氟沙星治疗临床效果显著,且不良反应少,安全性高,具有极高的临床应用及推广价值。
Objective To discuss the clinical effect of piperacillin sulbactam combined with levofloxacin in the treatment of elderly patients with pneumonia. Methods Selected from September 2012 to December 201499 cases of respiratory medicine study on effect of drug treatment in elderly patients with pneumonia,took different drug treatments,patients were randomly divided into three groups,Group A took piperacillin sulbactam combined with levofloxacin therapy,all patients in the control group got application of piperacillin sulbactam treatment,control group took levofloxacin therapy,observed and compared the efficacy and adverse reaction rates of three groups. Results Patients after treatment,the treatment group total effective rate was 96. 97%,control group 1 was 72. 73%,the control group was 75. 76%,2 group total effective rate was significantly higher than the control group 1 and 2,the data statistically significant differences in the two groups（ P〈0. 05）; Team total adverse reaction rate was 6. 06%,control group 1 was 3. 03%,the control group was 3. 03%,2 team total rate of adverse reaction similar to the control group 1 and 2,P〉0. 05,no statistical difference; Control group 1 and 2total effective rate and total rate of adverse reactions to contrast, P〉0. 05, no statistical difference.Conclusions The results showed that elderly patients with pneumonia taking piperacillin sulbactam combined with levofloxacin therapy,which has significant clinical effect and less side effects and is safe,with a high clinical application and promotion value.
出处
《齐齐哈尔医学院学报》
2015年第28期4215-4217,共3页
Journal of Qiqihar Medical University
