摘要
目的:观察中药治疗对肥胖相关性肾病患者生活质量指标的影响。方法:将113例肥胖相关性肾病患者随机分为对照组55例和治疗组58例,对照组给予生活方式干预、适当运动、饮食控制、厄贝沙坦口服等治疗。治疗组在对照组治疗基础上加用"健脾滋肾"中药方,治疗后比较两组治疗前后FBG、PBG、糖化血红蛋白、24小时尿蛋白定量、血肌酐、血脂、血尿素氮、血液流变学,血肌酐清除率、证候积分、生活质量评分的变化。结果:对照组在实验室指标和生活质量指标改善方面不明显。治疗组在实验室指标和生活质量指标改善方面均好于治疗前,治疗前后比较差异有统计学意义(P<0.05)。且明显优于对照组,差异有统计学意义(P<0.05)。结论:"健脾滋肾"中药治疗可改善肥胖相关性肾病患者实验室指标和生活质量。
Objective： To observe the effects on the living quality of obesity related glomerulopathy patients by Chinese drugs. Methods：113 cases of obesity associated glomerulopathy patients were randomly divided into control group 55 cases and 58 cases of treatment group,. The control group was given lifestyle intervention,appropriate exercise,diet control. The treatment group was given TCM prescription of tonifying spleen and nourishing kidney based on the control group. After the treatment,comparing the two groups,FBG,PBG,glycosylated hemoglobin,24 h urine protein quantitative,serum creatinine,blood lipid,blood urea nitrogen,blood rheology,blood creatinine clearance,syndrome integral,the change of quality of life score. Results： The control group in the aspect of laboratory index and quality of life index to improve is not obvious. Treatment group at the laboratory indexes and improvements in quality of life indicators are better than before the treatment,before and after treatment comparison difference was statistically significant（ P〈0. 05）. And obviously superior to control group,the difference was statistically significant（ P〈0. 05）. Conclusion： TCM prescription of tonifying spleen and nourishing kidney can improve the laboratory index and quality of life of patients with obesity related glomerulopathy.
出处
《中医学报》
CAS
2015年第10期1490-1492,共3页
Acta Chinese Medicine
基金
河北省科技计划支撑项目(12277789)
关键词
肥胖相关性肾病
健脾滋肾
生活质量
obesity related glomerulopathy
tonifying spleen and nourishing kidney
quality of life
