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超声可视化评价糖尿病性心肌病心肌电机械功能及血流动力学异常 被引量：1

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摘要 糖尿病是全世界发病率和致死率较高的慢性内分泌疾病。糖尿病性心肌病（diabetic cardiomyopathy,DCM）是糖尿病患者心肌细胞处于高糖、高脂环境下所引起的心脏并发症。自1974年Hamby等[1]首次提出DCM概念以来,DCM已被临床公认为糖尿病常见心脏并发症之一。DCM具有复杂的病理生理机制及电机械功能异常,因早期临床表现隐蔽而容易被忽视。
作者 马荣川 尹立雪
机构地区 四川医科大学附属医院超声科 四川省医学院科学院·四川省人民医院超声医学研究所
出处 《中华医学超声杂志（电子版）》 CSCD 2015年第8期611-614,共4页 Chinese Journal of Medical Ultrasound(Electronic Edition)
基金 四川省科研院所科技成果转化资金(11010122)
关键词 糖尿病性心肌病 机械功能 心肌运动 超声心动图技术 糖尿病大鼠 血流动力学 病理生理机制 心脏并发症 左心室内压 cardiomyopathy
分类号 R587.2 [医药卫生—内分泌]
  • 相关文献

参考文献33

  • 1Hamby RI, Zoneraich S, Sherman L. Diabetic cardiomyopathy[J]. JAMA, 1974, 229(13):1749-1754.
  • 2Mitrovic JPS, Seferovic PM, Tesic BV, et al. Predictors of diabetic cardiomyo- pathy in asymptomatic patients with type 2 diabetes [J]. Int J Cardiol, 2012, 156(2): 219-221.
  • 3Susic D, Varagic J, Ahn J, et al. Collagen cross-link breakers: a beginning of a new era in the treatment of cardiovascular changes associated with aging, diabetes, and hypertension [J]. Curr Drug Targets Cardiovasc Haematol Disord, 2004, 4(1): 97-101.
  • 4Inoguchi T, Sonta T, Tsubouchi H, et al. Protein kinase C dependent increase in reactive oxygen species (ROS) production in vascular tissues of diabetes: role of vascular NAD(P)H oxidase [J]. J Am Soc Nephrol, 2003, 14(8 Suppl 3): S227-S232.
  • 5Connelly KA, Kelly DJ, Zhang Y, et al. Inhibition of protein kinase C-beta by ruboxistaurin preserves cardiac function and reduces extracellular matrix production in diabetic cardiomyopathy [J]. Circ Heart Fail, 2009, 2(2): 129-137.
  • 6Pitocco D, Tesauro M, Alessandro R, et al. Oxidative stress in diabetes: implications for vascular and other complications [J]. Int J Mol Sci, 2013, 14(11): 21525-21550.
  • 7Ilkun O, Boudina S. Cardiac dysfunction and oxidative stress in the metabolic syndrome: an update on antioxidant therapies [J]. Curr Pharm Des, 2013, 19(27): 4806-4817.
  • 8Yang S, Chen C, Wang H, et al. Protective effects of Acyl-coA thioesterase 1 on diabetic heart via PPARa/PGClu signaling [J]. PLoS One, 2012, 7(11): e50376.
  • 9Casis O, Gallego M, Iriarte M, et al. Effects of diabeticcardiomyopathy on regional electrophysiologic characteristics of rat ventricle [J]. Diabetologia, 2000, 43(1 ): 101-109.
  • 10Panguluri SK, Tur J, Chapalamadugu KC, et al. MicroRNA-301a mediated regulation of Kv4,2 in diabetes: identification of key modulators [J]. PLoS One, 2013, 8(4): e60545.

二级参考文献69

  • 1佟艳明,李治安,何怡华,陈倬,谷孝艳,薛超.漩涡参数在左心室舒张功能评价中的应用[J].中华医学超声杂志（电子版）,2013,10(3):194-199. 被引量：2
  • 2张然,余志斌,王云英.成年小鼠心肌细胞分离技术[J].生理学报,2004,56(5):656-660. 被引量：21
  • 3张海锋,张博,张晓东,高峰.可视化动缘探测系统检测心肌细胞舒缩功能[J].中国应用生理学杂志,2004,20(4):410-414. 被引量：11
  • 4王云英,张然,余志斌.低压恒流灌流分离成年大鼠心肌细胞[J].中国应用生理学杂志,2005,21(4):475-479. 被引量：13
  • 5Barr EL,Zimmet PZ,Welborn TA,et al.Risk of cardiovascular and all-cause mortality in individuals with diabetes mellitus,impaired fasting glucose,and impaired glucose tolerance:The Australian Diabetes,Obesity,and Lifestyle Study (AusDiab).Circulation,2007,116:151-157.
  • 6Henry RM,Kamp O,Kostense PJ,et al.Left ventricular mass increases with deteriorating glucose tolerance,especially in women:independence of increased arterial stiffness or decr-eased flow mediated dilation:the Hoorn study.Diabetes Care,2004,27:522-529.
  • 7Grandi AM,Piantanida E,Franzetti I,et al.Effect of glycemic control on left ventricular diastolic function in type 1 diabetes mellitus.Am J Cardiol,2006,97:71-76.
  • 8Raman M,Nesto RW.Heart disease in diabetes mellitus.Endocrinol Metab Clin North Am,1996,25:425-438.
  • 9Jweied EE,McKinney RD,Walker LA,et al.Depressed cardiac myofilament function in human diabetes mellitus.Am J Physiol Heart Circ Physiol,2005,289:H2478-H2483.
  • 10Di Bonito P,Moio N,Cavuto L,et al.Early detection of diabetic cardiomyopathy usefulness of tissue Doppler imaging.Diabet Med,2005,22:1720-1725.

共引文献20

同被引文献32

  • 1佟艳明,李治安,何怡华,陈倬,谷孝艳,薛超.漩涡参数在左心室舒张功能评价中的应用[J].中华医学超声杂志（电子版）,2013,10(3):194-199. 被引量：2
  • 2Hamby RI, Zoneraich S, Sherman L. Diabetic cardiomyopathy[J]. JAMA, 1974, 229(13):1749-1754.
  • 3Mitrovic JPS, Seferovic PM, Tesic BV, et al. Predictors of diabetic cardiomyo- pathy in asymptomatic patients with type 2 diabetes [J]. Int J Cardiol, 2012, 156(2): 219-221.
  • 4Susic D, Varagic J, Ahn J, et al. Collagen cross-link breakers: a beginning of a new era in the treatment of cardiovascular changes associated with aging, diabetes, and hypertension [J]. Curr Drug Targets Cardiovasc Haematol Disord, 2004, 4(1): 97-101.
  • 5Inoguchi T, Sonta T, Tsubouchi H, et al. Protein kinase C dependent increase in reactive oxygen species (ROS) production in vascular tissues of diabetes: role of vascular NAD(P)H oxidase [J]. J Am Soc Nephrol, 2003, 14(8 Suppl 3): S227-S232.
  • 6Connelly KA, Kelly DJ, Zhang Y, et al. Inhibition of protein kinase C-beta by ruboxistaurin preserves cardiac function and reduces extracellular matrix production in diabetic cardiomyopathy [J]. Circ Heart Fail, 2009, 2(2): 129-137.
  • 7Pitocco D, Tesauro M, Alessandro R, et al. Oxidative stress in diabetes: implications for vascular and other complications [J]. Int J Mol Sci, 2013, 14(11): 21525-21550.
  • 8Ilkun O, Boudina S. Cardiac dysfunction and oxidative stress in the metabolic syndrome: an update on antioxidant therapies [J]. Curr Pharm Des, 2013, 19(27): 4806-4817.
  • 9Yang S, Chen C, Wang H, et al. Protective effects of Acyl-coA thioesterase 1 on diabetic heart via PPARa/PGClu signaling [J]. PLoS One, 2012, 7(11): e50376.
  • 10Casis O, Gallego M, Iriarte M, et al. Effects of diabeticcardiomyopathy on regional electrophysiologic characteristics of rat ventricle [J]. Diabetologia, 2000, 43(1 ): 101-109.

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中华医学超声杂志（电子版）
2015年 第8期

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