摘要
目的初步了解近年来我院骨科手术感染主要病原菌分布及其耐药性。方法采集骨科手术住院患者伤口分泌物样本进行细菌培养和药敏试验,并对结果进行分析。结果共收集分泌物样本323例,样本病原菌检出率为83.9%,以条件致病菌为主,其中革兰阴性菌占62.4%;药敏结果显示革兰阳性菌对青霉素和大环内酯类抗生素最低耐药率分别为88.3%和66.7%,革兰阴性菌对青霉素敏感性低(15.6%),上述两类菌都对万古霉素和碳氢霉烯类抗生素较敏感,最高耐药率分别为8.3%和44.4%。结论本院骨科术后感染主要以革兰阴性菌为主,对临床常规抗菌药物都出现不同程度耐药,仅对万古霉素和碳氢霉烯类抗生素较为敏感。
Objective To understand the development and distribution of the inflectional pathogens and their drug-resistance as a result of orthopedic surgery.Method Bacterial culture and sensitivity test were conducted on pathogens cultivated from the swab of wounds of the inpatients admitted to our hospital.Findings 323 specimens of swab were obtained.Pathogens were detected in 83.9% of the specimens during the experiment.Most of them were opportunistic pathogens and gram-negative bacteria accounted for 62.4%.The drug sensitivity tests showed that the rates of gram-positive bacteria’ s drug resistance to penicillin and macrolide antibiotics were 88.3%and 66.7%respectively.The drug sensitivity of gram-negative bacteria to penicillin was found as low as 15.6%.However, both gram-positive bacteria and gram-negative bacteria were found to be most sensitive to vancomycin and carbapenem antibiotics.Conclusion Gram-negative bacteria were the main inflectional pathogens resulting from orthopedic surgery, which had considerable resistance to various antibiotics.However, they were most sensitive to vancomycin and carbapenem antibiotics.
出处
《健康研究》
CAS
2015年第4期375-376,379,共3页
Health Research
关键词
骨科
外科感染
药敏分析
orthopedics
surgical infection
sensitivity analysis
