摘要
目的分析呼吸内科下呼吸道医院感染主要病原菌分布及耐药性,为临床治疗提供依据。方法回顾性分析2008-2010年呼吸内科下呼吸道医院感染患者痰培养分离的病原菌鉴定和药敏结果。结果共检出病原菌1024株,阳性率为36.9%,其中革兰阴性菌684株占66.8%,以铜绿假单胞菌、鲍氏不动杆菌、肺炎克雷伯菌为主;革兰阳性菌46株占4.5%,以金黄色葡萄球菌为主;真菌294株占28.7%,以白色假丝酵母菌为主,鲍氏不动杆菌耐药十分严重。结论革兰阴性菌为呼吸科下呼吸道医院感染的主要致病菌,对常用抗菌药物耐药率呈上升趋势,应加强临床细菌学的检测,根据药敏结果合理用药。
OBJECTIVE To explore the distribution and drug resistance characteristics of pathogens from nosocomial lower respiratory tract in respiratory medicine department to guide rational application of antibiotics.METHODS The pathogens isolated from sputum specimens of patients with nosocomial lower respiratory tract infection from 2008 to 2010 were identified and their drug resistance was analyzed.RESULTS A total of 1024 strains of pathogens were isolated,representing an isolation rate of 36.9%,in which G-bacilli accounted for 684 strains,ranking top one（66.8%）.The most common pathogens were Pseudomonas aeruginosa,Acinetobacter baumannii and Klebsiella pneumoniae.G＋ bacilli were 46 strains（4.5%）;the main pathogen was Staphylococcus aureus.Fungi were 294 strains（28.7%）,the main pathogen was Candida albicans.The drug resistance of A.baumannii was very serious.CONCLUSION G-bacilli are the main infectious pathogens causing lower respiratory tract infections and antibiotic resistance rates keep upward tendencg,so it is neccesary to intensify the detection of bacteriology and reasonably use antibiotics on the basis of drug susceptibilily testing.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2012年第5期1072-1074,共3页
Chinese Journal of Nosocomiology
关键词
下呼吸道感染
病原菌
耐药性
Lower respiratory tract infection
Pathogen
Drug resistance
