摘要
目的探讨肺保护性通气治疗急性呼吸窘迫综合征(ARDS)的临床疗效。方法将62例ARDS患者随机分为两组,其中对照组30例给予常规机械通气治疗,观察组32例给予肺保护性通气治疗,比较两组患者血氧分压(Pa O2)、二氧化碳分压(Pa CO2)、氧合指数(Pa O2/Fi O2)的变化情况以及带机时间、住院时间、呼吸机相关肺损伤(VALI)的发生率等。结果观察组患者经通气后8 h、24 h、48 h的Pa O2、Pa CO2、Pa O2/Fi O2均明显高于对照组(P<0.05),带机时间和住院时间均明显短于对照组(P<0.05),VALI发生率也明显低于对照组(P<0.05)。结论肺保护性通气能明显改善氧合,缩短带机时间和住院时间,减少VALI发生,对ARDS的临床救治具有重要意义。
Objective To evaluate the clinical effect of lung protective ventilation strategies on acute respiratory distress syndrome( ARDS). Methods 62 patients with acute respiratory distress syndrome were randomly divided into the control group( n = 30) and the observation group( n = 32). The control group was treated with conventional ventilation strategy,and the observation group was treated with lung protective ventilation strategies. Pa O2,Pa CO2,Pa CO2/ Fi O2 and ventilation time,hospitalization days and the rate of ventilator associated lung injury( VALI) were compared between the two groups. Results Pa O2,Pa CO2 and Pa O2/ Fi O2 at 8 h,24 h and 48 h after ventilation in the observation were signigicantly higher than those in the control group( P < 0. 05). The ventilation time,hospitalization days and the rate of VALI in the observation group were signigicantly shorter or lower than those in the control group( P < 0. 05). Conclusion Using lung protective ventilation strategies for acute respiratory distress syndrome can signigicantly shorten the ventilation time,hospitalization days and reduce the incidence of VALI. It has important clinical significance for ARDS.
出处
《中国临床新医学》
2015年第9期845-848,共4页
CHINESE JOURNAL OF NEW CLINICAL MEDICINE
关键词
肺保护性通气
急性呼吸窘迫综合征
临床疗效
Lung protective ventilation strategies
Acute respiratory distress syndrome(ARDS)
Clinical effect
