摘要
目的:探讨奥曲肽联合埃索美拉唑治疗肝硬化上消化道出血的临床疗效。方法:选取2012年2月-2015年2月苏州相城人民医院收治的肝硬化并发上消化道出血69例患者,随机分为对照组(n=34)和试验组(n=35),两组患者均给予补充血容量和一般性止血药等基础治疗,在此基础上对照组静脉滴注奥曲肽,试验组静脉滴注奥曲肽联合埃索美拉唑,观察两组患者的临床疗效。结果:与对照组相比,试验组患者的总有效率显著高,平均住院时间和不良反应率均显著低,两组比较差异均有统计学意义(P<0.05)。结论:奥曲肽联合埃索美拉唑治疗肝硬化合并上消化道出血,临床效果确切。
Objective：To investigate the effect of Octreotide combined with Esomeprazole in the treatment of liver cirrhosis with upper gastrointestinal hemorrhage.Method：69 patients with liver cirrhosis complicated with upper gastrointestinal hemorrhage were enrolled into this clinical trial from February 2012 to February 2015 at Suzhou Xiangcheng People’s Hospital,which were randomized into the control group（n=34） and test group（n=35） that were treated intravenously with octreotide alone and Octreotide combined with Esomeprazole following the basic treatment respectively. Result：Compared to the control group,a significant increase in total efficacy rate,a significant decrease in mean hospitalization time and a significant decrease in adverse reactions were observed for the test group,the differences were statistically significant（P＆lt;0.05）.Conclusion：It is concluded that Octreotide combined with Esomeprazole are beneficial in the treatment of liver cirrhosis complicated with upper gastrointestinal hemorrhage.
出处
《中外医学研究》
2015年第27期3-5,共3页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
肝硬化
上消化道出血
奥曲肽
埃索美拉唑
Liver cirrhosis
Upper gastrointestinal hemorrhage
Octreotide
Esomeprazole
