摘要
目的：探讨门诊中西药联合应用的合理性。方法：对2012年6月—2014年10月茂名市中医院门诊各科因中西药联合应用不合理导致的113例不良反应进行统计分析。结果：113例不良反应中,轻度54例（占47.79%）,中度31例（占27.43%）,重度28例（占24.78%）;年龄〈15岁患者39例（占34.51%）,15~60岁患者18例（占15.93%）,〉60岁患者56例（占49.56%）;中药注射剂与西药注射剂联合应用发生不良反应的病例数最多,为53例（占46.90%）,其次分别为中药固体剂与西药注射剂联合应用（26例,占23.01%）、中药注射剂与西药固体剂联合应用（18例,占15.93%）、中药固体剂与西药固体剂联合应用（16例,占14.16%）。结论：中西药联合应用是现阶段临床较有效的治疗方式,但配伍不合理也会降低药物安全性,发生不良反应。
OBJECTIVE： To study the rationality in combined use of traditional Chinese medicine and chemical medicine. METHODS： 113 adverse drug reaction（ ADR） cases induced by irrational combined use of traditional Chinese medicine and chemical medicine from June 2012 to October 2014 in Maoming Hospital of Traditional ChineseMedicine were statistically analyzed. RESULTS： Of the total 113 ADR cases,54（ 47. 79%） were mild,31 cases（ 27. 43%） moderate and 28 cases（ 24. 78%） severe. 39（ 34. 51%） aged 15 years,18（ 15. 93%） aged 15-60 years and 56（ 49. 56%） aged 60 years. The ADRs induced mostly by combined use of traditional Chinese medicine and chemical medicine with 53 cases（ 46. 90%）,followed by combined use of solid traditional Chinese medicine and chemical medicine injections（ 26 cases,accounted for 23. 01%）,combined use of traditional Chinese medicine injection and solid chemical medicine（ 18 cases,accounted for 15. 93%） and combined use of solid traditional Chinese medicine and solid chemical medicine（ 16 cases,accounted for 14. 16%）. CONCLUSIONS： Combined use of Chinese patent medicine and chemical medicine is currently an effective therapy,but their irrational combination may reduce the drug safety and induce adverse drug reactions.
出处
《中国医院用药评价与分析》
2015年第7期974-976,共3页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
中成药
西药
联合应用
不良反应
合理用药
Chinese patent medicine
Chemical medicine
Drug combination
Adverse drug reaction
Rational use of drugs
