摘要
目的:探讨副肿瘤性边缘叶脑炎(PLE)的MRI特征。方法:回顾性分析8例经临床诊断治疗的PLE的临床及MRI资料。所有患者均行常规MRI平扫及DWI检查,其中6例行增强扫描。结果:18例病变分布均以海马及海马旁回为主,其中3例可见病变同时累及双侧杏仁核、2例累及双侧扣带回、1例累及左侧岛叶、1例累及桥脑。病变双侧对称分布7例,单侧发病1例。2信号特征:6例病变于T1WI上呈较均匀稍低信号,T2WI呈高信号,DWI呈稍高或等信号;2例于T1WI呈等信号,T2WI呈稍高信号,DWI呈等信号;所有病灶在FLAIR图像上均呈高信号。6例行增强扫描,5例病变无强化,1例可见小片状轻度强化。结论:PLE具有较典型的临床及MRI特征,应结合抗体检测及其它全身检查,积极寻找原发肿瘤进行综合治疗。
Objective：To investigate the MR features of paraneoplastic limbic encephalitis （PLE）.Methods：The clini-cal and MRI data of 8 cases with PLE were retrospectively analyzed.All patients underwent plain MRI and DWI scan,6 of them also underwent post-contrast MRI study.Results：①Hippocampus and parahippocampal gyrus were involved in all ca-ses,the bilateral amygdala was also involved in 3 cases,the bilateral cingulate gyri in 2 cases,the left insula in one case and the pons in one case.The lesions distributed bilateral symmetrically in 7 cases,unilateral in one case.②MRI signal changes：prolonged T1 and T2 signal,or restricted diffusion on DWI in 6 cases,isointensity on T1 WI and DWI,slight hyperintensity on FLAIR images.Six cases underwent post-contrast MRI study,only one case had mild enhancement.Conclusion：PLE had typical MRI characteristics,we should combine antibody testing and other systemic examinations,to seek the primary tumor and treat it comprehensively.
出处
《放射学实践》
北大核心
2015年第8期802-805,共4页
Radiologic Practice
关键词
边缘叶脑炎
副肿瘤综合征
临床特征
磁共振成像
Limbic encephalitis
Paraneoplastic syndromes
Clinical features
Magnetic resonance imaging
