摘要
目的：探讨心肌血流储备分数（FFR）对冠状动脉分叉病变缺血的预测价值。方法：经冠脉造影（CAG）证实需植入支架的分叉病变患者30例随机分为FFR指导经皮冠脉介入治疗组（FFR-PCI组）及常规CAG后介入治疗组（CAG-PCI组）,FFR-PCI组支架植入前后对主支及边支血管行FFR测定,对FFR〈0.75的病例行介入治疗,CAG-PCI组根据造影结果和经验行介入治疗,比较两组支架植入数量,并随访6~9月观察主要不良心血管事件（MACE）发生率。结果：与CAG-PCI组相比,FFR-PCI组的支架植入个数较少,且MACE发生率较低,差异具有统计学意义（P〈0.05）。结论：对冠脉分叉病变患者行FFR测定有助于制定合理的手术策略,不仅减少支架植入,而且降低MACE发生率。
Objective ： To investigate the application value of fraction flow reserve （FFR） for ische- mia induced by bifurcation coronary artery lesion. Method： Thirty patients with bifurcation lesion, di- agnosed to require stent implantation through coronary angiography, were randomly assigned into FFR- PCI Group and regular CAG-PCI Group. In FFR-PCI group, FFR of both main vessels and side bran- ches were measured before and after the stent implantation, and the intervention treatment was per- formed on patient with FFR less than O. 75 ; in CAG-PCI group, the intervention treatment was per- formed based on coronary angiography; all patients were followed up for 6 to 9 months and major ad- verse cardiovascular event （MACE） was observed. Result： Compared with CAG-PCI group, less stent were implanted into patients of FFR-PCI group, and MACE occurrence rate of FFR-PCI group was sig- nificantly lower then that of CAG-PCI group （P 〈 0.05 ）. Conclusion： FFR measured before and after the stent implantation for bifurcation coronary artery lesion can be used to accurately identify and de- sign a reasonable surgical strategy. In this way, the number of stent implanted can be reduced and the MACE incidence rate can be decreased.
出处
《贵阳医学院学报》
CAS
2015年第9期1008-1009,1012,共3页
Journal of Guiyang Medical College
基金
延安大学附院课题(2012YDFY-Y304)
关键词
冠状动脉
分叉病变
血流储备分数
介入治疗
coronary artery
bifurcation lesions
fraction flow reserve
intervention
