摘要
目的分析小剂量芬太尼联合丙泊酚静脉麻醉在胃镜检查中的应用价值。方法选择2012年12月-2013年12月接受胃镜检查的患者作为研究对象,随机分为小剂量芬太尼联合丙泊酚麻醉的观察组患者以及咪达唑仑联合丙泊酚麻醉的对照组患者,检测其麻醉后入睡时间、苏醒时间、丙泊酚总用量、不良反应及应激反应等情况。结果观察组患者麻醉后的入睡时间、苏醒时间明显短于对照组患者,且丙泊酚总用量明显少于对照组患者(P<0.05)。观察组患者麻醉后的总不良反应发生率明显低于对照组患者(P<0.05)。观察组患者麻醉后的各项炎症因子水平及应激指标水平均显著低于对照组患者(P<0.05)。结论小剂量芬太尼联合丙泊酚静脉麻醉可以有效缩短胃镜检查患者的诱导及苏醒时间,减少麻醉药物用量,且可减少检查中不良反应发生,有效减轻炎症应激反应。
【Objective】To analyze the effect of small doses fentanyl combined with propofol intravenous anesthesia on patients undergoing gastroscopy. 【Methods】Patients undergoing gastroscopy between October 2012 to October 2013 were chosen as research subjects, randomly divided into observation group with smaller doses fentanyl combined with propofol anesthesia and control group with midazolam combined with propofol. The sleep time, wake time and total propofol dosage, adverse reactions, stress control in two groups were recorded and compared. 【Results】The sleep and recovery time after anesthesia in observation group were significantly shorter than that in control group, total amount of propofol was significantly less（ P〈0.05）. After anesthesia, the observation group patient＇s incidence of adverse reactions was significantly lower（ P〈0.05）. The inflammatory factors and stress index levels in observation group were significantly lower（ P〈0.05）. 【Conclusion】Low doses of fentanyl combined with propofol intravenous anesthesia can effectively shorten the induction and recovery time of patients with gastroscopy, reduce the narcotic drugs amount and incidence of adverse reactions, and effectively restrain inflammation stress reaction.
出处
《中国内镜杂志》
北大核心
2015年第7期746-748,共3页
China Journal of Endoscopy
关键词
胃镜
芬太尼
丙泊酚
gastroscopy
fentanyl
propofol
