摘要
目的:观察清瘟败毒饮治疗脓毒症急性肾损伤的临床疗效。方法:将120例患者随机分为治疗组与对照组,每组各60例。对照组给予常规西药治疗,治疗组在对照组基础上予清瘟败毒饮口服或鼻饲治疗。结果:两组患者在治疗前中医证候评分、APACHE II评分、Scr、BUN、CRP比较,无明显差异(P>0.05);治疗后两组患者Scr、BUN均上升,治疗组比对照组上升幅度减小,差异具有统计学意义(P<0.05);治疗后两组患者中医证候评分、APACHE II评分、CRP均减小,但治疗组减小幅度增大(P<0.05);治疗组有效为81.67%,对照组有效率为63.33%,两组有效率比较,差异有统计学意义(P<0.05)。结论:清瘟败毒饮能改善脓毒症急性肾损伤患者中医症候评分和临床有效率,降低APACHE II评分。
Objective： To observe the clinical curative effect of Decoction for Eliminating Pestilence and Sepsis on acute kidney damage due to sepsis. Methods： One hundred and twenty patients were randomly divided into the treatment group and the control group,with 60 cases in each group. The patients in the control group were given routine Western medical treatment,while the ones in the treatment group were also given Decoction for Eliminating Pestilence and Sepsis for oral administration or nasal feeding on the treatment basis of the control group. Results： Before the treatment,in terms of TCM syndrome score,APACHE II score,Scr,BUN and CRP,there was no obvious different difference between the two groups（ P 〈0. 05）. After the treatment,the Scr and BUN in both groups increased; The rising range of the treatment group was smaller than that of the control group; And the difference between them had statistical meaning（ P 〉0. 05）. After the treatment,TCM syndrome score,APACHE II score and CRP decreased; The decreased range of the treatment group was larger than that of the control group（ P 〈0. 05）. The effective rate of the treatment group was 81. 67%,while that of the control group was 63. 33%; And the difference between them had statistical meaning（ P 〈0. 05）. Conclusion： Decoction for Eliminating Pestilence and Sepsis can improve TCM syndrome score and the clinical curative rate of patients with acute kidney damage due to sepsis and reduce their APACHE II score.
出处
《河南中医》
2015年第6期1392-1394,共3页
Henan Traditional Chinese Medicine
基金
国家中医药管理局"十二五"重点专科建设项目(编号:ZJ0901JZ015)
上海市卫生局中医药科研基金(编号:20102062A)
关键词
脓毒症
肾损伤
清瘟败毒饮
sepsis
kidney damage
Decoction for Eliminating Pestilence and Sepsis
