阻塞性睡眠呼吸暂停综合征患者轻度认知功能障碍的MoCA评估被引量：5

Mo CA evaluation in obstructive sleep apnea syndrome patients with mild cognitive impairment

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摘要目的探讨简易精神状态检查量表(MMSE)、蒙特列尔认知评估量表(Mo CA)评估阻塞性睡眠呼吸暂停综合征(OSAS)患者轻度认知功能障碍(MCI)的可行性。方法用便携式多导睡眠仪、MMSE及Mo CA对51名OSAS患者和35名单纯鼾症者进行睡眠监测和认知功能的评价。结果 OSAS组Mo CA评分结果为21.1±3.0,显著低于对照组的25.0±2.6(P<0.01);MMSE评分结果在OSAS组与对照组中分别为27.8±1.8及28.1±1.7,无统计学意义。结论 Mo CA对于OSAS患者MCI的早期诊断敏感性优于MMSE,对于MMSE测试结果正常但高度怀疑存在MCI者,Mo CA是一种简便可行的筛查工具。 Objective Obstructive sleep apnea syndrome （OSAS） is known to be associated with impairment in cognitive function.The aim of this study is to develop a sensitive screening tool to detect mild cognitive impairment （MCI） among Chinese patients with OSAS.Methods There were totally 51 OSAS patients （OSAS group） and 35primary snoring peoples （control group） included in the study.All of them were monitored by polysomnography （PSG）,administered by the mini-mental state examination （MMSE） and the Montreal cognitive assessment （MoCA） questionnaires was applied to assess their sleep condition and cognitive function.Results Compared with control group,the score of MoCA in OSAS group was 21.1 ± 3.0,strikingly lower than that of the control group 25.0 ±2.0（P ＜0.01）,the scores of MMSE in OSAS group and control group were 27.8 ± 1.8 and 28.1 ± 1.7,the difference was of no significance.Conclusions The MoCA is a simple and sensitive tool for the assessment of MCI in OSAS patients,whose performance on the MMSE is in the normal range.

作者王前刘丽梅林永忠

机构地区大连医科大学附属第二医院神经内科

出处《基础医学与临床》 CSCD 2015年第7期956-958,共3页 Basic and Clinical Medicine

关键词阻塞性睡眠呼吸暂停轻度认知功能障碍神经心理学测试 obstructive sleep apnea syndrome mild cognitive impairment neuropsychological test

分类号 R766 [医药卫生—耳鼻咽喉科]

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1Baldwin CM, Griffith KA, Nieto FJ, et al. The association of sleep disordered breathing and sleep symptoms with qual- ity of life in the sleep heart health study [J]. Sleep,2001, 24:96-105.
2Albert MS,Dekosky ST, Dickson D,et al. The diagnosis of mild cognitive impairment due to Alzheimer's disease: recom- mendations from the national institute on aging-Alzheimer as- sociation workgroups on diagnostic guidelines for Alzheimer's disease [J]. Alzheimer's Dement,2011,7:270-279.
3Grandjean J, D'O Stilio K, Phillips C, et al. Modulation of brain activity during a stroop inhibitory task by the kind of cognitive control required[ J]. PLoS One,2012,7 :e41513. doi : 10. 1371/journal. pone. 0041513.
4Luis CA, Keegan AP, Mullan M. Cross validation of the montreal cognitive, assessment in community dwelling older adults residing in the southeastern US [ J ]. Int J Geriatr Psychiatry ,2009, 24 : 197-201.
5Fujiwara Y, Suzuki H, Yasunaga M, et al. Brief screening tool for mild cognitive impairment in older Japanese: valida- tion of the Japanese version of the Montreal Cognitive As- sessment[J]. Geriatr Gerontol Int,2010, 10:225-232.
6Yu J, Li J, Huang X. The Beijing version of the montreal cognitive assessment as a brief screening tool for mild. cogni- tive impairment : a community-based study [ J ]. BMC Psy- chiatry,2012, 12 : 156. doi : 10.1186/1471-244x- 12-156.
7姚燕,杨芳,王丽娟,郭蔚莹,张天一,李波,袁晓洁,修明.蒙特利尔认知评估量表在轻度认知功能障碍诊断中的应用[J].吉林大学学报（医学版）,2012,38(4):730-735. 被引量：40
8Chen R, Xiong KP, Huang JY, et al. Neurocognitive im- pairment in Chinese patients with obstructive sleep apnea hypopnea syndrome[ J]. Respirology, 2011,16:842-848.
9Lamer AJ. Screening utility of the montreal cognitive as- sessment(MoCA) : in place of or as well as the MMSE? [ J ]. Int Psychogeriat,2012,24 : 391- 396.