摘要
目的探讨德令哈市成人麻疹发病的相关影响因素,为该地区成人麻疹防控提供参考。方法采用病例对照研究的方法 ,收集德令哈市50例成人麻疹病例和100例健康对照人群为研究对象,面对面询问收集该人群的人口特征学、生活行为史、麻疹疫苗免疫史等信息。采用多因素logistic方法进行相关因素分析。结果已婚、流动人口、集体宿舍居住、经常熬夜和有麻疹患者接触史是麻疹发病的独立危险因素（OR值分别为5.359、5.356、6.295、5.261和13.583,95%CI分别为1.776-16.053、1.879-15.265、1.809-21.903、1.152-24.028、1.868-98.774）,接种麻疹疫苗是麻疹发病的保护因素（OR=0.103,95%CI=0.030-0.357）,且随着接种次数的增多,保护效应逐渐增强（接种1次：OR=0.285,95%CI=0.100-0.807;接种2次及以上：OR=0.025,95%CI=0.002-0.288）。结论流动人口、集体宿舍居住、经常熬夜和有麻疹患者接触史等特征人群可能是成人麻疹发病的高危因素,而接种麻疹疫苗是麻疹发病的保护因素,增加疫苗接种针次,有助于降低麻疹发病危险。
Objective To explore the influencing factors of adult measles for the clues in prevention of epidemic disease in Delhi.Methods Information about general social-demographic characteristics,lifestyle behaviors and the immunization history of measles vaccine were collected by face-to-face interview among 50 adult measles cases and 100 controls in Delhi.Multivariate logistic regression was used to analyze the risk factors of adult measles.ResultsMultivariate logistic regression analysis indicated that marriage,floating population,living in dormitory,frequently staying up late and the history of contact measles cases were risk factors of measles infection in adults（the odds ratio[OR ]5.359,5.356,6.295,5.261 and 13.583,95% confidence interval [95%CI ]）1.776-16.053,1.879-15.265,1.809-21.903,1.152-24.028 and 1.868-98.774,respectively）.However,vaccinated measles vaccine as a protective measure can help reduce the infection of measles for adults.The protective effect of measles vaccine was gradually strengthened with the increase of injection times（OR value of vaccinated 1and 2doses measles vaccine 0.285and0.025,95%CI =0.100-0.807 and 0.002-0.288,respectively）.Conclusion Floating population,living in dormitory,frequently staying up late and the history of contact measles cases may be the high risks to infect measles.But fortunately,vaccinated against measles was thought as a protective factor to reduce the incidence and mortality of measles in adults with the increase of injection times.
出处
《临床荟萃》
CAS
2015年第7期789-792,共4页
Clinical Focus
