摘要
目的探讨黄甘颗粒对尖锐湿疣(CA)患者血清IFN-γ,IL-2水平的影响情况及对其抑制复发的作用。方法将入选的58例CA患者随机分为两组,各29例,全部患者予CO2激光术治疗,治疗组同时还予黄甘颗粒1粒(组分:黄芪30g,紫草15g,黄柏和甘草各10g)口服,3次/d,连用30d。结果两组患者治疗前、后血清IFN-γ和IL-2水平差异均有统计学意义(P均<0.05)。出院后3个月时,治疗组复发3例,对照组复发9例,差异也有统计学意义(P<0.05)。结论黄甘颗粒可提高血清IFN-γ和IL-2水平,对CA治疗和抑制复发有较好的临床疗效。
Objective To determine whether Huanggan Granules influence the levels of serum 1FN-γ and IL-2, and inhibit the recurrence of condyloma acuminatum （CA）. Method 58 patients with CA were randomly divided into two groups, 29 cases per group. All patients were treated with CO2 laser. Following laser treatment, the treatment group were also orally given HuangGan Granules （ containing radix astragali 30 g, radix lithospermi 15 g, cortex phellodendri 10 g, radix glyeyrrhizae 10 g） 3 times daily for 30 days. Result In both groups, the levels of serum IFN-γ and IL-2 changed significantly following treatment （ P 〈 0.05 ）. Three months after discharge from hospital, the recurrence rates were significantly different between treated and contols （3 patients in treated group vs. 9 in controls, P 〈 0.05）. Conclusion Huanggan Granules can elevate the levels of serum IFN-γ and IL-2, and exhibit therapeutic benefit and prevent the recurrence of CA.
出处
《中国皮肤性病学杂志》
CAS
CSCD
北大核心
2015年第6期595-596,共2页
The Chinese Journal of Dermatovenereology
