期刊文献+

调控成骨细胞分化影响因子的研究进展

原文传递
导出
摘要 哺乳动物的骨骼处在骨形成和骨溶解的平衡中,这两个过程分别由成骨细胞和破骨细胞介导。成骨细胞可由间充质干细胞经过前成骨细胞发育而来,这个过程受到许多细胞因子的调控,包括促进成骨和抑制成骨。本篇综述主要介绍在成骨细胞分化过程中发挥重要调节作用的细胞因子。
出处 《现代免疫学》 CAS CSCD 北大核心 2015年第3期254-256,253,共4页 Current Immunology
基金 国学自然科学基金(30972743 81373208) 上海市科委基础研发重点项目(11JC1411602) 上海市教委科研创新重点项目(12ZZ103)
  • 相关文献

参考文献26

  • 1van der KraanPM, Blaney Davidson EN, van den Berg WB. A role for age-related changes in TGFbeta signaling in aber rant chondrocyte differentiation and osteoarthritis[J]. Ar thritis Res Ther,2010,12:201-210.
  • 2Deng ZL, Sharff KA, Tang NI, et al. Regulation of osteo- genic differentiation during skeletal development[J]. FrontBiosci, 2008, 13: 2001-2021.
  • 3Crane JL, Cao X. Bone marrow mesenchymal stem cells and TGF-Ⅱ signaling in bone remodeling[J]. J Clin Invest, 2014, 124: 466-472.
  • 4Miyazono K, Maeda S, Imamura T. BMP receptor signaling: transcriptional targets, regulation of signals, and signaling cross-talk[J]. Cytokine Growth factor Revi, 2005, 16 : 251- 263.
  • 5Takada I, Kouzmenko AP, Kato S. Molecular switching of osteoblastogenesis versus adipogenesis: implications for tar- geted therapies[J], expert Opin Ther Targets, 2009: 593- 603.
  • 6Bennett CN, Longo KA, Wright WS, et al. Regulation of osteoblastogenesis and bone mass by Wntl0b[J]. Proce Nat Acad Sci USA, 2005, 102: 3324-3329.
  • 7Takada I, Mihara M, Suzawa M, et al. A histone lysine methyltransferase activated By non-canonical wntsignalling suppresses PPAR-y transactivation[J]. Nat Cell Biol, 2007, 9: 1273-1285.
  • 8Baksh D, Boland GM, Tuan RS. Cross - talk between Wnt signaling pathways in human mesenchymal stem cells leads to functional antagonism during osteogenicdifferentiation[J]. J Cell Biochem, 2007, 101: 1109-1124.
  • 9Hayrapetyan A, Jansen JA, van den Beucken JJJP. Signaling pathways involved in osteogenesis and their application for Bone Regenerative Medicine[J]. Tissue Engin Part B: Rev, 2015,21:75-87.
  • 10Zellin G, Linde A. Effects of recombinant human fibroblast growth factor-2 on osteogenie cell populations during orthopi- eosteogenesis in vivo[J]. Bone, 2000, 26: 161-168.

二级参考文献21

  • 1Tack C J, Kleijwegt FS, Van Riel PL, et al. Development of type 1 diabetes in a patient treated with anti-TNF-alpha ther- apy for active rheumatoid arthritis [J]. Diabetologia, 2009, 52,1442-1444.
  • 2Ko JM,Gottlieb AB,Kerbleski JF. Induction and exacerbation of psoriasis with TNF-blockade therapy:a review and analysis of 127 cases [J]. Dermatolog Trea,2009,20..100-108.
  • 3Horiuchi T, Mitoma H, Harashima S, et al. Transmembrane TNF-alpha : structure, function and interaction with anti-TNF agents [J]. Rheumatology, 2010,49 : 1215-1228.
  • 4Faustman D, Davis M. TNF receptor 2 pathway drug target for autoimmune diseases [J]. Nature Rev Drug Discov,2010, 9 : 482-493.
  • 5Chen X, Subleski JJ, Kop{ H, et al. Cutting edge : Expression of TNFR2 defines a maximally suppressive subset of mouse CD4 Jr- CD25 + Foxp3 T regulatory cells: applicability to tumor-infiltrating T regulatory cells [J]. J Immunol, 2008, 180:6467-6471.
  • 6Nagar M,Jacob Hirsch J,Vernitsky H,et al. TNF activates a NF B-regulated cellular program in human CD45RA- regula- tory T ceils that modulates their suppressive function [J]. J Immunol, 2010,184 : 3570-3581.
  • 7Vignali DA, Collison LW, Workman CJ. How regulatory T cells work [J]. Nat Rev Immunol,2008,8:523-532.
  • 8van Mier[o GJ, Scherer HU, Hameetman M, et ag. Cutting edge:TNFR-shedding by CD4+ CD25+ regulatory T cells in hibits the induction of inflammatory mediators [J]. J Immu nol,2008,180:2747 2751.
  • 9Boschetti G,Nancey S,Sardi F,etal. Therapy with anti-TNFalpha antibody enhances number and function ot" Foxp3 regulatory T cells in inflammatory bowel diseases [J]. Inflamm Bowel Dis,2011,17 160-170.
  • 10Chen X, Murakami T,Oppenheim JJ,et aZ. Differential re sponse of murine CD4+ CD25+ and CD4 CD25 T cells to dexamethasone-induced cell death [J]. Eur J Immunol,2004, 34 : 859-869.

共引文献6

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部