摘要
目的探讨采用英国胸科协会改良肺炎评分(confusion,uremia,respiratory,BP,age 65 years,CURB-65评分)对慢性阻塞性肺疾病急性加重期(chronic obstructive pulmonary disease with acute exacerbation,AECOPD)患者住院期间的预后进行预测的临床价值。方法回顾性分析本院本院呼吸内科收治的134例AECOPD患者的临床资料,根据CURB-65评分进行分组,探讨CURB-65评分法对患者住院期间预后的预测价值。结果死亡组的CURB-65评分、急性生理与慢性健康评分(acute physiology and chronic health evaluation,APACHE)Ⅱ评分、机械通气时间、多器官功能障碍综合征发生率均显著长于或高于生存组(P<0.05)。CURB-65评分、APACHEⅡ评分法对患者病情分级的一致性检验Kappa=0.841、P=0.000。CURB-65评分、APACHEⅡ评分的受试者工作特征曲线(receiver operating characteristic curve,ROC曲线)下面积(area under curve,AUC)分别为0.808、0.842,两种评分方法的AUC值比较差异无显著性(Z=0.549,P=0.218)。结论与APACHEⅡ评分相比,CURB-65评分同样能够对AECOPD患者的预后进行较为准确的判定,且具有简单、方便操作的优点。
Objective To investigate the scores by British thoracic society score （ confusion,uremia,respiratory,BP, age 65 years,CURB-65 score） improved pneumonia on acute exacerbation of chronic obstructive pulmonary disease （ AECOPD） clinical value of patients during hospitalization prognosis prediction. Method Retrospective analysis of the clinical data of 134 cases of AECOPD patients in our hospital from respiratory department of internal medicine, according to the CURB-65 score group, to explore the predictive value of CURB-65 score in prognosis of patients during hospitalization. Result Death group CURB-65 score, acute physiology and chronic health evaluation（ Acute physiology and chronic health evaluation, APACHE II） score, duration of mechanical ventilation, multiple organ dysfunction syndrome （ Multiple organ dysfunction syndrome, MODS） incidence of significant longer or higher than the survival group （P〈0. 05）. CURB-65 score, APACHE II score on the patient＆#39;s condition grading consistency test Kappa=0. 841, P=0. 000. The area under the ROC curve was CURB-65 score：AUC = 0. 808, APACHEIIscore：AUC = AUC value of 0. 842 difference between the two scoring methods was not significant （Z=0. 549, P=0. 218）. Conclusion Compared with APACHEII score, CURB-65 score on the prognosis of patients with AECOPD is also able to conduct a more accurate determination, and has a simple, easy to operate advantage.
出处
《中国医刊》
CAS
2015年第3期65-68,共4页
Chinese Journal of Medicine
关键词
英国胸科协会改良肺炎评分
慢性阻塞性肺疾病急性加重期
预测
临床价值
British thoracic society score improved pneumonia
Chronic obstructive pulmonary disease with acute exacerbation
Forecasting
Clinical value
