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尿脱落细胞学检查应用于原发性输尿管癌诊断的临床研究 被引量:2

Clinical research of urinary exfoliocytology examination in the diagnosis of primary carcinoma of ureter
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摘要 目的 探究尿脱落细胞学检查对于原发性输尿管癌的诊断价值.方法 回顾性分析2006年1月至2013年6月间来我院就诊的原发性输尿管癌患者62例,先经CT检查,再经尿脱落细胞学检查,最后所有患者均取样进行组织病理学诊断,比较分级、分期,并进行统计学评价.结果 尿脱落细胞学检查的总阳性率为85.5%,肿瘤分级为G1级69.2%和(G2 ~ G3)级94.4%,分期为(Ta ~ T1)期65.7%和(T2~T4)期88.9%,均高于CT检查,组间差异有统计学意义(P<0.05);新鲜尿样诊断的准确率为79.0%,高于晨尿样本,但是晨尿样本中有4例未在新鲜尿样本中检出.结论 与CT检查相比,尿脱落细胞学检查的准确率更高,特别是在高分级和高分期肿瘤的阳性率更高,是一个值得深入研究的临床诊断方法. Objective To discuss the diagnostic value of urinary exfoliocytology examination in primary carcinoma of ureter.Methods 62 cases of primary carcinoma of ureter in our hospital from Jan.2006 to Jun.2013 were retrospectively analyzed.All patients underwent CT and urinary exfoliocytology examination,pathological diagnosis with samples taken.Compared grades and stages.Results The overall positive rate of urinary exfoliocytology examination was 85.5%,69.2% for tumor grade G1,94.4% for tumor grade G2-G3,65.7% for tumor stage T0-T1,and 88.9% for tumor stage T2-T4,which were all higher than those of CT examination,with statistically significant differences (P〈0.05).The diagnostic accuracy of fresh-urine samples was 79.0%,higher than that of morning-urine samples.4 cases of morning-urine samples were not checked out in fresh-urine samples.Conclusion The accuracy rate of urinary exfoliocytology examination in primary carcinoma of ureter is higher than that of CT examination,especially among higher tumor grades and stages.Urinary exfoliocytology examination is a clinical diagnosis method worthy of further study.
作者 孙启耀
出处 《国际医药卫生导报》 2015年第10期1439-1442,共4页 International Medicine and Health Guidance News
关键词 尿脱落细胞学检查 原发性输尿管癌 诊断 Urinary exfoliocytology examination Primary carcinoma of ureter Diagnosis
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