摘要
目的探讨血清肿瘤标志物癌胚抗原(CEA)、糖类抗原125(CA125)、神经元特异性烯醇化酶(NSE)、细胞角蛋白21-1片段(CYFRA21-1)在非小细胞肺癌预后判断中的价值。方法选择2010年3月至2013年3月收治的178例非小细胞肺癌患者,按照疾病进展时间(TTP)分为5组。结果各组间NSE、CYFRA21-1和CEA含量差异无统计学意义(P>0.05)。各组间的CA125含量差异有统计学意义(P<0.05)。CEA、CYFRA21-1和CA125水平与患者的1年生存率有关。结论血清肿瘤标志物CEA、CA125、NSE和CYFRA21-1在非小细胞肺癌的预后判断中具有一定的应用价值。
Objective To explore the value of serum tumor markers of carcinoembryonic antigen （CEA） , carbohydrate antigen 125 （ CA125 ）, neuron specific enolase （ NSE）, cytokeratin fragment 21-1 （ CY- FRA21-1 ） in the judgment of prognosis of non-small-cell carcinoma. Methods 178 cases of patients with non-small-cell carcinoma from May 2010 to May 2013 were selected, and were divided into five groups accord- ing to the time to progression （TIP）. Results The levels of NSE,CYFRA21-1 and CEA in each group had no significant difference（P 〉0. 05）. The levels of CA125 in each group were significantly different（P 〈0. 05）. There was a relationship between the CEA,CYFRA21-1 ,CA125 levels and one-year survival rate. Condusion It has application value of serum tumor markers in judging the prognosis of non-small-cell carcinoma.
出处
《中国肿瘤临床与康复》
2015年第5期529-531,共3页
Chinese Journal of Clinical Oncology and Rehabilitation
