摘要
目的探讨慢性肾功能衰竭患者血清铁蛋白与血脂的相关性。方法比较正常对照组及慢性肾功能衰竭(CRF)组血清铁蛋白(SF)、总蛋白(TP)、白蛋白(ALB)、同型半胱氨酸(Hcy)以及总胆固醇(TC)、甘油三酯(TG)、载脂蛋白AI(APOAI)、载脂蛋白B(APOB)、脂蛋白(a)[Lp(a)]、高密度脂蛋白胆固醇(HDL-C)和低密度脂蛋白胆固醇(LDL-C)水平。结果 CRF组血清SF、Hcy、TG、TC、LDL-C、Lp(a)浓度均显著高于对照组(P=0.001),而TP、ALB、HDL-C和APOAI水平均显著低于对照组(P=0.025)。对照组中SF与ALB呈正相关(P=0.029);CRF组中SF与TG呈正相关(P=0.009),与APOAI呈负相关(P=0.008)。结论 CRF血清SF与其脂类代谢异常有关。
Objective To explore the correlation between serum ferritin and lipids in patients with chronic renal failure（ CRF）. Methods Serum levels of ferritin（ SF）,total protein（ TP）,albumin（ ALB）,homocysteine（ Hcy） and total cholesterol（ TC）,triglyceride（ TG）,Apo lipoprotein AI（ APOAI）,Apo lipoprotein B（ APOB）,lipoprotein（ a） [Lp（ a） ],high-density lipoprotein cholesterol（ HDL-C） and low-density lipoprotein cholesterol（ LDL-C）） were compared between control group and CRF group. Results The levels of SF,Hcy,TG,TC,LDL-C and Lp（ a）of the CRF group were significantly higher than those of the control group（ P = 0. 001）,and levels of TP,ALB,HDL-C and APOAI were significantly lower than those of the control group（ P = 0.025）. In the control group,the SF was positively correlated with ALB（ P = 0. 029）. In the CRF group,the SF was positively correlated with TG（ P = 0. 009）,and it was negatively correlated with APOAI（ P = 0. 008）. Conclusion The SF is correlated with the abnormalities of lipid metabolism in patients with CRF.
出处
《实用临床医药杂志》
CAS
2015年第7期77-79,共3页
Journal of Clinical Medicine in Practice
关键词
慢性肾功能衰竭
铁蛋白
血脂
chronic renal failure
ferritin
serum lipids
