摘要
目的探讨急性重症心肌炎患者血浆脑钠肽(BNP)检测的临床意义。方法对98例急性重症病毒性心肌炎患者进行血管紧张素转化酶血浆脑钠肽水平的检测,与112例健康体检者进行比较,并且对各类型急性重症病毒性心肌炎患者血浆脑钠肽的浓度进行比较。结果急性重症病毒性心肌炎患者血浆脑钠肽的浓度为(298.56±97.53)pg/L,健康对照组的血浆脑钠肽的浓度为(64.82±19.26)pg/L,急性重症病毒性心肌炎患者血浆脑钠肽水平显著高于对照组,差异有统计学意义(P<0.01)。急性重症心肌炎患者的症状不同,BNP浓度的变化不一样。症状轻的患者BNP与对照组相比差异无统计学意义(P>0.05),而症状严重患者(如心梗患者组)与对照组比较,BNP升高明显,差异有统计学意义(P<0.01)。结论 BNP可以作为急性重症心肌炎患者诊断的辅助指标,具有临床诊断的实际意义。
Objective The clinical significance of serum BNP in patients with acute severe viral myocarditis was discussed in this paper. Methods Chemiluminescence was applied to measuring serum BNP for 98 acute severe viral myocarditis patients and compared with 112 health check-up people. The BNP was measured for acute severe viral myocarditis patients with different symptom. Results Serum BNP concentration was significantly elevated in patients with acute severe viral myocarditis（298. 56 ± 97. 53） pg/L compared with the control group（64. 82 ± 19. 26） pg/L,serum BNP levels of acute severe viral myocarditis patients were significantly higher than that of the control group（ P〈0. 01）. The serum BNP was different in acute severe viral myocarditis patients with different symptom. Compared with the control group,the difference between BNP in mild symptom group and the control group had no statistical significance（ P〉0. 05）,while the BNP in severe symptom group,such as myocardial infarction,increased significantly（ P〈0. 01）. Conclusion Serum BNP can be an assistant index to the acute severe viral myocarditis and has clinical significance.
出处
《中国卫生检验杂志》
CAS
2015年第7期1020-1021,1024,共3页
Chinese Journal of Health Laboratory Technology
