摘要
目的研究医院多重耐药菌的分布特点及耐药性,为临床采取多重耐药菌感染控制措施及抗菌药物的选用提供科学依据。方法通过开展细菌耐药目标性监测,对某医院2012年住院患者送检标本分离出的多重耐药菌株和药敏试验结果进行统计分析。结果全年共检出病原菌1 505株,其中多重耐药菌554株,检出率为36.81%,其中耐甲氧西林金黄色葡萄球菌143株,占25.8%;产超广谱β-内酰胺酶(ESBLs)肠杆菌科细菌167株,占30.1%;多重耐药/泛耐药铜绿假单胞菌72株,占13.0%;耐碳青霉烯鲍曼不动杆菌108株,占19.5%;耐万古霉素肠球菌10株,占1.8%;嗜麦芽窄食单胞菌54株,占9.7%。554株多重耐药菌分离自下呼吸道、泌尿道、皮肤软组织、血液等,分别占73.8%、8.5%、7.9%、4.0%。结论多重耐药菌是医院感染的主要致病菌,医疗机构应采取综合有效措施进行预防和控制。
Objective To investigate the distribution and drug susceptibility of multidrug- resistant（ MDR） of one hospital in 2012,so as to provide basis for the control of bacterial resistance and the reasonable use of antibiotics. Methods Data of multiple drug- resistant from 2012 in the hospital were reviewed by statistics methods. Results Totally 1 505 strains of pathogens were isolated in 2012,554 strains were MDR,the isolated rate was 36. 81%. Of them 143（ 25. 8%）strains were methicillin- resistant Staphylococcus aureus,167（ 30. 1%） strains were β lactamases（ ESBLs） producing Enterobacteriaceae,72（ 13. 0%） strains were pan- drug and multi resistant of Pseudomonas Aeruginosa,108（ 19. 5%）strains were Carbapenem- resistant Acinetobacter Baumannii,10（ 1. 8%） strains were Vancomycin- resistant Enterococcus and 54（ 9. 7%） strains were Stenoortphomonas maltophilia. The lower respiratory tract,urinary tract,skin soft tissue and blood were the main specimen sources,which accounting for 73. 8%,8. 5%,7. 9% and 4. 0% respectively. Conclusion The multi- drug resistant bacteria are the main pathogens in the hospital. The comprehensive measures of prevention and control should be taken.
出处
《中国消毒学杂志》
CAS
北大核心
2015年第2期130-132,共3页
Chinese Journal of Disinfection
关键词
多重耐药菌
院内感染
耐药性
multidrug-resistant organisms
nosocomial infection
drug resistance
