摘要
以聚乙烯醇(PVA)和壳聚糖(CS)为主要原料,采用物理交联与化学交联相结合的制备工艺,即通过循环冷冻—解冻法结合京尼平交联法,制备了具有互穿网络结构(IPN)的聚乙烯醇/壳聚糖复合水凝胶,并分别通过红外光谱(FTIR)和扫描电子显微镜(SEM)表征了其分子结构和形态结构;探讨了不同制备工艺对复合水凝胶溶胀性能的影响,并将其与单一原料常规工艺制备的水凝胶作对比.结果表明,与单一原料常规工艺制备的水凝胶相比,具有IPN结构的水凝胶在溶胀性能上表现出更好的稳定性.最佳制备工艺为京尼平用量4%,反应温度55℃,冷冻—解冻循环3次.
The interpenetrating networks（IPNs） hydrogels based on poly（ vinyl alcohol）（PVA） and chitosan（CS） were prepared through physical-chemical cross-linking process. During this process, physical cross-linking for PVA was undertaken by circle freezing-thawing technique and chemical cross-linking was induced by a natural and nontoxic cross-linking agent, genipin. The physical/chemical interreaction between PVA and CS was confirmed vis Fourier transform infrared spectroscopy （FTIR）, the morphology of PVA/CS IPNs hydrogels was investigated by scanning electron microscope（SEM）. The results of swelling experiments revealed that,PVA/CS IPNs hydrogels had better comprehensive （mechanical-swelling） properties than that formed by single process and single preparation process. The optimum conditions for the preparation of PVA/CS IPNs hydrogels posing the best comprehensive properties were as follows：the dosage of genipin was 4% （mGP/mCS）, the cross-linking reaction temperature was 55℃ and the cycle freezing-thawing times was three.
出处
《西南民族大学学报（自然科学版）》
CAS
2015年第2期186-191,共6页
Journal of Southwest Minzu University(Natural Science Edition)
基金
西南民族大学中央高校基本科研业务费专项基金一般项目"聚乙烯醇基医用敷料的开发"(2014NYB03)
西南民族大学研究生创新科研一般项目(CX2013SP02)
关键词
互穿网络
聚乙烯醇
壳聚糖
水凝胶
溶胀性能
interpenetrating networks （IPNs）
PVA, chitosan
hydrogel
swelling
