摘要
目的研究快速和慢速扩弓对正畸牙齿龈沟液中碱性磷酸酶表达变化的影响。方法采用Hass矫治器进行快速或慢速扩弓,每组患者各15例,平均年龄10.2岁。在扩弓前(基线),扩弓后1周,保持1、4、8、12周,记录上颌第一前磨牙牙龈指数(GI)、牙周探诊深度(PD),通过全自动生化分析仪检查碱性磷酸酶水平。结果两组临床指标除在加力后第1周牙龈指数有统计学差异外,其余观察时间点无显著差异。碱性磷酸酶含量在加力后第1周到保持阶段第4周,快速扩弓组高于慢速扩弓组,之后慢性扩弓组缓慢升高,到保持第8周,两组无统计学差异,在第12周两组仍未恢复到基线水平。结论碱性磷酸酶可能参与了扩弓后牙周组织的改建,在慢性扩弓组,龈沟液中ALP表达较持续,可能更有利于牙周组织的改建。
Objective To investigate effects of rapid and slow maxillary expansion protocols on the levels of alkaline phosphatase （ALP）. Methods Thirty patients（ mean age 10.2 years） were randomly divided into 2 groups：rapid maxillary expansion group（ n = 15 ） and slow maxillary expansion group（ n = 15 ） via Hass appliance. ALP activity was measured by a full automatic biochemical analy- zer at the following time points： before activation, 1 week after activation, lweek,4 weeks, 8 weeks, 12 weeks in retention period. The clinical parameters,gingival index（GI） and periodontal depth （PD）were also recorded accordingly. Results No statistical difference was found between the two groups in terms of GI and PD with the exception of GI at 1 week after activation. ALP levels were significant- ly higher in rapid maxillary expansion group than those in slow maxillary expansion group from 1 week after activation to 4 weeks in re- tention,but there was no significant difference between the two groups after 8 weeks in retention. Conclusions ALP in gingival crevic- ular fluid may he involved in the periodontal tissue remodeling, and the slow maxillary expansion could result in light and continuous force which might be more favorable to periodontal tissue.
出处
《口腔医学》
CAS
2015年第2期101-103,共3页
Stomatology
基金
南京市医学科技发展基金(YKK10049)
南京医科大学科技发展基金(2012NJMU057)
关键词
碱性磷酸酶
上颌扩弓
龈沟液
alkaline phosphatase
maxillary expansion
gingival crevicular fluid
