摘要
目的：了解湖南省肿瘤医院（以下简称“我院”）肿瘤患者发生药品不良反应（ ADR）的特点和规律。方法：收集我院2012—2013年上报的393例ADR报告，按患者年龄、性别、所涉及的药品种类、给药途径、累及器官和（或）系统及临床表现等进行统计分析。结果：41～65岁中老年患者ADR发生率较高（297例，占75.5％）；抗肿瘤药（98例，占24.9％）、中药注射剂和中成药（54例，占13.7％）、免疫调节剂（43例，占10.9％）发生ADR的例数居前3位；给药途径以静脉滴注为主（382例，占97.2％）；51.8％（213例次）的患者表现为全身性症状。结论：医院需重视临床用药合理性，加强ADR监测工作，降低药品使用的风险。
OBJECTIVE：To investigate the characteristics and patterns of adverse drug reactions（ ADR） in patients from Hunan Provincial Tumor Hospital （ hereinafter referred to as “our hospital”） .METHODS： 393 ADR cases collected in our hospital from 2012 to 2013 were analyzed statistically in terms of patients’ gender and age, drug types, route of administration, organ or system involved in ADR and clinical manifestation.RESULTS： Among 393 ADR cases, the elder patients aged 41-65 years showed the highest proportion （ 297 cases,75.5%）; the ADR were induced mostly by antineoplastics（98 cases,24.9%）, followed by traditional Chinese medicine injections（54 cases, 13.7%） and immunomodulators（ 43 cases,10.9%）; intravenous drip infusion was the main route of administration （382 cases, 97.2%）; 51.8%（ 213 cases ） manifested as systemic symptoms.CONCLUSIONS： Great importance should be attached to rational use of drugs and ADR monitoring so as to reduce the risk of drug use.
出处
《中国医院用药评价与分析》
2014年第11期1038-1041,共4页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
药品不良反应
肿瘤患者
分析
Adverse drug reaction
Tumor patient
Analysis
