摘要
目的 探讨自动乳腺全容积扫描（automated breast volume scanner,ABVS）冠状面汇聚征对乳腺浸润性导管癌（infiltrating ductal carcinoma,IDC）治疗敏感性及其预后的预测价值.方法 选取于本院行乳腺癌根治性切除术、病理诊断为IDC的患者46例,共47个病灶,分析病灶ABVS冠状面汇聚征与其临床病理[病灶大小、病理组织学分级、腋窝淋巴结状态以及雌激素受体（ER）、孕激素受体（PR）、人表皮生长因子受体（HER2）表达]的相关性.结果 汇聚征在不同大小和不同腋窝淋巴结状态IDC组中出现比例差异无统计学意义（P＞0.05）.汇聚征在病理分级Ⅱ级组中出现的比例高于Ⅲ级组,差异有统计学意义（P=0.008）.汇聚征在ER阳性组出现的比例高于ER阴性组,但差异无统计学意义（P=0.055）;在PR阳性组出现的比例高于PR阴性组,差异有统计学意义（P=0.004）;在HER2阴性组出现的比例高于HER2阳性组,差异有统计学意义（P=0.019）.结论 汇聚征对IDC治疗敏感性及其预后有一定的预测价值.
Objective To explore the value of convergence symptom in predicting the treatment sensitivity and the prognosis of patients with breast infiltrating ductal carcinoma （IDC）.Methods A retrospective review was performed in 46 women with 47 IDC lesions.Correlation between clinicopathological characteristics and convergence symptom was analyzed.Clinicopathological characteristics included tumor size,tumor grade,axillary lymph node state and the expression of ER,PR and H ER2.Results There was no obvious difference within different IDC groups by tumor size or axillary lymph node state in the presentation of convergence symptom （P ＞ 0.05）.The convergence symptom was more common in grade Ⅱ IDC lesions than in grade Ⅲ IDC lesions and the difference was statistically significant （P =0.008）.No difference was found between the presentation of convergence symptom and the expression of ER （P =0.055）.Significant correlations were found between the presentation of convergence symptom and the expression of PR and HER2 （P ＜0.05）.Conclusions Convergence symptom is helpful in predicting the treatment sensitivity and the prognosis of patients with breast infiltrating ductal carcinoma.
出处
《中华超声影像学杂志》
CSCD
北大核心
2014年第12期1057-1060,共4页
Chinese Journal of Ultrasonography
基金
国家自然科学基金（81371577）
关键词
超声检查
癌
导管
乳腺
汇聚征
Ultrasonography,mammary
Carcinoma,ductal,breast
Convergence symptom
