摘要
目的 分析阻塞性睡眠呼吸暂停低通气综合征（OSAHS）对脑卒中的影响。方法 选取2013年10月~2014年9月江苏省徐州医学院附属医院50例脑卒中伴OSAHS作为研究组,55例不伴OSAHS的脑卒中患者作为对照组,比较两组患者多导睡眠图、睡眠结构、认知功能和嗜睡程度的差异。结果 与对照组比较,研究组患者AHI明显增高,夜间平均动脉血氧饮合度（Sa O2）降低、夜间最低Sa O2下降明显、夜间呼吸事件明显增多,觉醒时间、N1期及N2期延长,N3期、REM期时间缩短,MMSE评分下降,ESS评分增高,差异均有统计学意义（均P〈0.05）。结论 脑卒中伴OSAHS患者夜间缺氧及睡眠结构紊乱症状严重,认知功能下降,白日嗜睡明显。
Objective To analyze the impact of obstructive sleep apnea syndrome（OSAHS） on the stroke. Methods50 stroke patients with OSAHS from October 2013 to September 2014 in the Affiliated Hospital of Xuzhou Medical College were selected as study group, 55 stroke patients without OSAHS were selected as control group. The differences of polysomnography sleep architecture, cognitive function and degree of sleepiness between two groups were compared.Results Compared with control group, the patients in the study group have significantly higher AHI, lower average Sa O2 at night, significantly lower minimum Sa O2, increased respiratory events at night, wake time, stage N1 and stage N2 were extended, stage N3 and rapid eye movement（REM） were shortened, MMSE score decreased and ESS score increased,the differences were statistically significant（P〈0.05）. Conclusion Stroke patients with OSAHS have the symptom of severe nocturnal hypoxia and structural disorder of sleep, cognitive decline and obvious daytime sleepiness.
出处
《中国医药导报》
CAS
2014年第36期62-65,共4页
China Medical Herald
基金
江苏省徐州市科技计划一般项目(编号XM13B044)
