摘要
目的探讨不孕症妇女在生活和工作环境中接触的可能危险因素。方法采用病例对照研究，于2012年10月8日—2013年1月8日在北京大学第三医院门诊进行问卷调查，内容包括个人基本情况、个人生活习惯、环境中接触到的可疑危险因素等情况。确诊不孕症为不孕组，回收有效问卷352例；同期自然妊娠孕妇为对照组，回收有效问卷413例。结果单因素分析显示，被动吸烟、吃油炸食品、用塑料制品饭盒、不经常体育锻炼、经常使用香水、指甲油、染发、烫发、熬夜、肥胖、有毒有害化学物、噪声接触、粉尘接触、长期在空调环境中工作、居室不常通风、居住地环境不佳对不孕有影响；非条件多因素Logistic回归分析表明，文化程度高、失眠（OR=2．6，95％CI：1．7～4．O）、吃油炸食品（OR=2．0，95％CI：1．2—3．3）、月经不规律（OR=3．1，95％CI：1．8～5．3）、有粉尘接触史（OR=2．4，95％ CI：1．0～5．6）、居住地环境质量差（OR=1．9，95％CI：1．4～2．7）为不孕症的危险因素。结论女性不孕症的发生与自身疾病、生活习惯和环境接触的危险因素有关。对育龄女性加强宣教针对性，减少上述危险因素的接触，可预防不孕的发生。
Objective To explore risk factors of female infertility with emphasis of work and environment exposures. Methods From October 8, 2012 to January 8, 2013, we conducted a questionnaire survey at the outpatient service in Peking University Third Hospital. The questionnaire included demographic information, personal habits, and exposure to some environmental factors. We took the female infertility as case group （ n = 352）, while the natural pregnant women as control group （ n = 413）. Results Univariate analysis revealed that two groups were different in some life style and environmental factors such as second-hand smoking, fried food intake, perfume use, working in the air-conditional environment, lack of exercises and some other factors. Unconditional Logistic regression analysis showed that the higher level of education, insomnia （ OR = 2.6, 95 % CI： 1.7 - 4. 0）, irregular menstruation （ OR = 3. 1, 95 % CI： 1.8 - 5. 3 ） , fried foods （ OR = 2.0, 95 % CI： 1.2 - 3.3 ） , the poor environmental residence （ OR = 1.9, 95 % CI： 1.4 - 2.7 ） and some other factors were risk factors for female infertility. Conclusion Female infertility is associated with life style and environmental factors. Reproductive health education should target these factors to reduce the risk of female infertility.
出处
《中国生育健康杂志》
2014年第6期505-509,共5页
Chinese Journal of Reproductive Health
关键词
不孕症
环境
危险因素
病例对照研究
Infertility
Environment
Risk factors
Case-control study
