头皮发际区微针疗法对血管性痴呆患者认知功能及同型半胱氨酸的影响被引量：9

Effect on the Cognitive Ability and Hcy of Patients with Vascular Dementia Treated by Micro-acupuncture in the Hairline Regions of Scalp

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摘要目的:探讨头皮发际区微针疗法治疗血管性痴呆(VD)的疗效。方法:80例VD患者随机分为两组。观测组用头皮发际区微针疗法,对照组用口服药物疗法。用循环酶法检测血浆同型半胱氨酸(Hcy)的浓度,采用MMSE和ADL量表评定患者的认知功能、社会活动功能及日常生活能力。结果:两组疗效比较:观测组的总有效率为62.50%,对照组的总有效率为55.00%,二者差异有显著性意义(P<0.05),治疗后两组MMSE、ADL量表评分与治疗前自身比较均有显著改善(P<0.01);治疗后,观测组的MMSE、ADL量表评分与对照组相比较改善更为明显(P<0.05);两组血浆Hcy水平治疗后较治疗前自身比较均有显著下降(P<0.01);治疗后,观测组血浆Hcy水平与对照组比较,下降更为明显(P<0.05)。结论:头皮发际区微针疗法对于VD患者具有确切疗效,其治疗机理与降低血浆Hcy水平相关。 Objective：To evaluate the efficacy of patients with vascular dementia （ VD） treated by micro-acupuncture in the hairline regions of scalp.Methods：80 cases of VD were treated by micro-acupuncture in the hairline regions of the scalp.Before and after treatment, the changes about Plasma Homocysteine （ Hcy） , MMSE and ADL rating scale were examined for evaluating patients′cognitive function and activities of daily living.Results：The effective rate of observa-tion group （62.50%）was higher than that of control group（55.00%）（P〈0.05）;After treatment,the MMSE and ADL scores in two groups were improved significantly（P〈0.01）;the MMSE and ADL scores of observation group were im-proved better than that of control group（P〈0.05）.After treatment ,the Hcy levels in two groups were decreased signifi-cantly（P〈0.01）;the Hcy levels of observation group were decreased more than that of control group （P〈0.05）. Conclusion：The micro-acupuncture in the hairline regions of the scalp is an effective therapy for VD and its therapeutic mechanism may be related closely to reducing Hcy levels in blood.

作者牛文民刘智斌杨晓航王渊

机构地区陕西中医学院第一附属医院针灸科

出处《中医药学报》 CAS 2014年第5期79-81,共3页 Acta Chinese Medicine and Pharmacology

基金陕西省科技厅项目(批准号:2010K15-01)

关键词血管性痴呆头皮发际区微针疗法同型半胱氨酸 Vascular dementia Micro-acupuncture in the hairline regions of the scalp Homocysteine

分类号 R246.6 [医药卫生—针灸推拿学]

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参考文献13

1Roman G C. Vascular dementia may be the most common form of de- mentia in the elderly[ J]. J Neurol Sci,2002,4:7 -10.
2Murray M E, Knopman D S, Dickson D W. Vascular dementia: clin- ical, neuroradiologic and neuropathologic aspects [ J ]. Panminerva Med,2007,49 (4) : 197 - 207.
3冯德琳,张倩,孙远征.头穴丛刺为主治疗血管性痴呆的临床研究[J].中医药信息,2014,31(4):139-141. 被引量：14
4American Psychiatric Association. Diagnostic and statistical manual of mental disorders ( DSM - IV) [ M]. Washington: American Psychiat- ric Association, 1994 : 143 - 147.
5Roman G C, Tatemiehi T K, Erkinjuntti T, et al. Vascular dementi- a: diagnostic criteria for research studies - Report of the NINDS - AIREN International Workshop[ J ]. Neurology, 1993,43:250 - 260.
6中华人民共和国卫生部.中药新药治疗痴呆的临床研究指导原则[S].北京:人民卫生出版社,1995:206-209.
7牛文民.头皮发际区穴位分布全息律.美国中华医药杂志,2000,6(5):75-76.
8刘智斌,牛文民.头皮发际区微针系统[J].中国针灸,2010,30(6):522-524. 被引量：27
9Conri C, Constans J, Parrot F, et al. Inverted question mark homocys- teinemia: role in vascular disease [ J ]. Presse Med, 2000,29 ( 13 ) : 658 - 660.
10Lindgreen A, Brattatrom L, Norring B, et al,Plasma homocysteine in acute and convalescent phases after stroke [ J ]. Stroke, 1995,26 (6) : 7981 - 7982.