摘要
目的分析艾迪注射液联合GP化疗方案对非小细胞肺癌患者血管新生指标和免疫功能指标的影响。方法选择四川省资阳市第一人民医院接受治疗的128例非小细胞肺癌患者作为研究对象,随机分为接受单纯GP化疗方案治疗的对照组及接受艾迪注射液联合GP化疗方案治疗的观察组,各64例。比较治疗前后两组患者的血清VEGF水平、免疫球蛋白水平、T细胞亚群水平的差异。结果观察组患者接受联合治疗后的VEGF各项指标值均显著低于对照组患者(P<0.05)。观察组患者接受治疗后的IgG、IgA、IgM水平均显著高于对照组患者(P<0.05)。观察组患者接受治疗后的CD4+、CD4+/CD8+水平明显高于对照组患者(P<0.05),CD8+水平低于对照组患者(P<0.05)。结论艾迪注射液联合GP化疗方案可以有效降低非小细胞肺癌患者的血清VEGF水平,提升机体免疫功能。
【Objective】To analyze the effect of Aidi injection combined with GP chemotherapy on non-small cell lung cancer patients＇ angiogenesis and immune function indicators. 【Methods】128 patients with non-small cell lung cancer were enrolled, and randomly assigned to control group received GP chemotherapy and observation group accepted aidi injection combined with GP chemotherapy. The VEGF levels, immunoglobulin levels, T cell subsets level in two groups were compared.【Results】The serum VEGF levels in Observation group after combination therapy were significantly lower than that in control group patients（P〈0.05）. The levels of IgG, IgA, IgM in observation group were significantly higher than that in control group（P〈0.05）. The levels of CD4＋, CD4＋/CD8＋in observation group were significantly higher, and CD8＋levels were lower than that in control patients（P〈0.05）.【Conclusions】Aidi injection combined with GP chemotherapy can reduce angiogenesis index value of non-small cell lung cancer and significantly enhance immune function.
出处
《中国现代医学杂志》
CAS
CSCD
北大核心
2014年第24期40-43,共4页
China Journal of Modern Medicine
关键词
非小细胞肺癌
艾迪注射液
化疗
non-small cell lung cancer Aidi injection chemotherapy
