摘要
目的 探讨肝硬化患者院内感染的危险因素。方法 选择2013年2月~2014年2月在解放军425医院就诊的肝硬化患者109例,检测患者血清学、血生化指标,对临床资料进行整理,使用非条件二元Logistic回归模型对肝硬化患者院内感染危险因素进行分析。结果 肝硬化感染组患者年龄,住院天数明显多于肝硬化无感染组患者,肝硬化组患者介入性操作,合并糖尿病,合并肝癌,Child-pugh分级C级,有消化道出血史患者的例数明显大于肝硬化无感染组,且差异有统计学意义（P≤0.05）。年龄,住院天数,介入性操作,合并糖尿病,合并肝癌,Child-pugh分级C级,消化道出血史经单因素分析可纳入Logistic回归模型,Logistic回归分析结果显示年龄（OR=4.163）,住院天数（OR=3.168）,介入性操作（OR=2.674）,合并糖尿病（OR=2.965）,合并肝癌（OR=3.689）,Child-pugh分级C级（OR=4.952）,消化道出血史（OR=5.674）为肝硬化合并院内感染的危险因素。结论 应采取措施消除肝硬化合并院内感染的危险因素。
Objective To investigate the risk factors of nosocomial infection in patients with cirrhosis. Methods The risk factors of nosocomial infection in 109 cirrhosis cases were investigated from February 2013 to February 2014 and the results were statistically analyzed using non-conditional logistic regression model. Results The age and duration of hospitalization of cirrhosis patients with nosocomial infection were significantly higher than cirrhosis case without nosocomial infection. The number of cases with interventional procedure, complicated with diabetes and hepatocellular carcinoma, with Grade C of Child-pugh,with the history of gastrointestinal bleeding were significantly more than number of patients without nosocomial infection, showing statistically significant difference （P ≤ 0.05）. Logistic regression analysis showed that age （OR = 4.163）, days of hospitalization （OR = 3.168）, interventional procedures （OR = 2.674）, diabetes （OR = 2.965）, hepatocellular carcinoma （OR = 3.689）, Child-pugh grade C （OR = 4.952）, history of gastrointestinal bleeding （OR = 5.674） were the risk factors for nosocomial infections in cirrhosis cases. Conclusion Measures be adopled to eliminate the risks factor for nosocomial infection in cirrhosis partients
出处
《中国热带医学》
CAS
2014年第8期978-980,共3页
China Tropical Medicine
