摘要
目的观察川崎病患儿医院感染的危险因素,以积累经验,为临床工作提供支持。方法回顾性分析2004年1月-2012年12月250例川崎病患儿临床资料,对感染患儿医院感染发生部位、危险因素、病原菌种类及药敏试验进行分析,数据采用SASS6.12软件进行处理。结果 250例川崎病患儿共发生医院感染44例,感染率为17.60%;感染部位以肺部为主33例占75.0%;共检出病原菌70株,革兰阴性杆菌40株占57.14%,革兰阳性菌28株占40.00%,真菌2株占2.86%;年龄、住院时间延长、长时间应用激素及抗菌药物是增加医院感染的危险因素(P<0.05);金黄色葡萄球菌、溶血葡萄球菌对万古霉素100.0%敏感;铜绿假单胞菌、肺炎克雷伯菌对亚胺培南100.0%敏感。结论川崎病患儿住院期间应强化医院感染的控制,若患儿出现医院感染,应积极进行细菌学监测,同时关注危险因素,并积极进行治疗。
OBJECTIVE To observe the risk factors and drug sensitivity characteristics in children with Kawasaki disease,so as to provide theoretical help for clinical work.METHODS Clinical data from 250 cases of Kawasaki disease（from Jan.2004 to Dec.2005）were reviewed to perform an analysis on the infective sites,risk factors,pathogen species and drug sensitivity characteristics with SASS6.12.RESULTSIn the 250 children with Kawasaki disease,there were 44 infective cases（17.60%）,mainly pulmonary infections（33cases,75.0%）.A total of 70 strains of pathogens were found,including 40 strains of gram-negative bacilli（57.14%）,28 strains of grampositive bacilli（40.00%）and two strains of fungi（2.86%）.Age,long duration of hospitalization,adrenal cortical hormone and prophylactic antibiotics application were risk factors of nosocamial infections（P〈0.05）.Staphylococcus aureus and Staphylococcus haemolyticus were sensitive to vancomycin（sensitivity 100.0%）.Pseudomonas aeruginosa and Klebsiella pneumoniae were sensitive to imipenem（sensitivity 100.0%）.CONCLUSIONChildren with Kawasaki disease should receive strengthened prevention of nosocommial infections.If infection occurred,active measures should be taken on bacterial test,risk factors and treatment.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2014年第19期4885-4886,4889,共3页
Chinese Journal of Nosocomiology
基金
丽水市公益性技术应用研究基金项目(20095917)
关键词
川崎病
医院感染
病原菌
药敏分析
Kawasaki disease
Nosocomial infection
Pathogen
Drug sensitivity test
