摘要
维甲酸(RA)对肾间质纤维化(RIF)存在着重要的影响,Notch信号途径在肾纤维化中发挥了关键作用,本文就维甲酸对肾纤维化与Notch通路的影响进行综述,探索维甲酸干预Notch途径能否成为新的抗肾纤维化策略。
The effect of retinoic acid （RA） on renal interstitial fibrosis （RIF） is important. Notch signaling is known to play an important role in the pathological injury of RIF. This study summarized recent research progress of the effect of RA on RIF and Notch signaling. Interruption of Notch signaling by RA might be a potential anti-fibrotic strategy in RIF.
出处
《天津医药》
CAS
北大核心
2014年第9期956-960,共5页
Tianjin Medical Journal
关键词
维甲酸
NOTCH信号
肾间质纤维化
retinoic acid
Notch signaling
renal interstitial fibrosis
