摘要
目的研究小儿慢性鼻-鼻窦炎的病原微生物分布及其药物敏感试验情况。方法 95例慢性鼻-鼻窦炎伴腺样体肥大的小儿行腺样体切除术,术中在鼻窦内窥镜下用消毒棉拭子取上颌窦口和后组筛窦口的分泌物,分别进行细菌的培养及药物敏感实验。结果 89份标本有细菌生长,所有标本中细菌培养阳性率为93.7%,其中需氧菌86株,厌氧菌28株。95例患儿需氧菌感染81例,厌氧菌感染52例,混合感染44例。药物敏感试验显示,对需氧菌抗菌活性较高的是阿莫西林克拉维酸;对厌氧菌抗菌活性较高的是甲硝唑。结论儿童慢性鼻-鼻窦炎以需氧菌感染为主,细菌感染在儿童慢性鼻窦炎中的作用较大,对于儿童慢性鼻-鼻窦炎,抗菌药物有较好的疗效。
Objective To investigate the distribution of pathogenic bacteria in children with chronic rhinosinusitis （CRS） and their susceptibility to commonly used antibacterial drugs .Methods 95 cases of CRS complicating adenoidal hypertrophy were per-formed adenoidectomy .The secretion of maxillary sinus ostium and posterior ethmoid sinus ostium was collected during endoscopic adenoidectomy by the disinfected cotton swab for conducting the bacterial culture and the drug sensitivity test .Results 89 speci-mens showed the bacterial growth ,the positive rate of bacterial culture in all culture specimens was 93 .7% ,86 strains of aerobic bacteria ,28 strains of anaerobic bacteria .Among 95 patients ,81 cases of aerobic infection ,52 cases of anaerobic infection ,44 cases of mixed infection .The drugs susceptibility test in vitro displayed that amoxicillin and clavulanate potassium had the higher antibacte-rial activity to aerobic bacteria and metronidazole had the higher antibacterial activity to anaerobic bacteria .Conclusion Children CRS is dominated by the aerobic bacterial infection .The bacterial infection plays a larger role in children CRS .Antibacterial drugs have better effect for treating CRS .
出处
《重庆医学》
CAS
CSCD
北大核心
2014年第27期3580-3581,3620,共3页
Chongqing medicine
基金
重庆市卫生局面上项目(08-2-190)
关键词
小儿
鼻窦炎
细菌
药物敏感试验
children
rhinosinusitis
bacteria
drug susceptibility test
