摘要
目的：探讨阿立哌唑联合社交技能训练对慢性精神分裂症临床疗效的影响。方法将100例慢性精神分裂症患者随机分为两组，每组50例。两组均予以阿立哌唑治疗，研究组在此基础上联合社交技能训练。观察8周。于治疗前后采用阳性与阴性症状量表、护士用住院病人观察量表、住院精神病人康复疗效评定量表评定临床疗效。结果治疗后两组阳性与阴性症状量表、精神疾病康复疗效评定量表总分均较治疗前显著降低（P＜0．01），研究组较对照组下降更显著（P＜0．01）；护士用住院病人观察量表总分较治疗前显著升高（P＜0．01），研究组较对照组升高更显著（P＜0．01）。结论阿立哌唑合并社交技能训练能显著改善慢性精神分裂症患者的精神症状和社交能力，提高其生活质量，最大程度地减轻精神残疾，促进患者顺利回归社会。
Objective To explore the effect of aripiprazole plus social skill training in chronic schizophrenia （CS） .Methods A total of 100 CS patients were randomly divided into two groups of 50 ones each .Both groups were treated with aripiprazole ,on this basis research group was plus social skill training for 8 weeks .Clinical efficacies were assessed with the Positive and Negative Syndrome Scale （PANSS） ,Nurses , Observation Scale for Inpatient Evaluation （NOISE） and IPROS before and after treatment .Results Af-ter treatment the PANSS and IPROS total scores of both groups lowered more significantly compared with pre-treatment （P〈 0 .01） ,so did those in research than control group （P〈 0 .01）;after treatment the NOISE total score heightened more significantly compared with pre-treatment （P〈0 .01） ,so did those in research than control group （P〈 0 .01） .Conclusion Aripiprazole plus social skill training could signifi-cantly improve mental symptoms and sociability ,raise quality of life ,lessen mental disability in the grea-test degree and promote patients’ return to society smoothly .
出处
《临床心身疾病杂志》
CAS
2014年第5期84-86,共3页
Journal of Clinical Psychosomatic Diseases
基金
南宁市科学技术局科研资助项目（编号ZC2010008C）
