摘要
目的探讨无创正压通气(NPPV)对急性心源性肺水肿(ACPE)患者的临床治疗价值。方法将65例ACPE患者随机分为对照组(30例)与观察组(35例),对照组接受常规治疗,观察组在此基础上加用NPPV治疗,记录观察2组患者的呼吸困难、粉红色泡沫样痰及肺部湿罗音等症状体征的改善时间,并比较2组患者治疗前后的呼吸频率、心率、血压等生命体征;氧分压、二氧化碳分压、血氧饱和度等血气指标。结果治疗前2组无显著差异,治疗后观察组的症状改善时间显著短于对照组,生命体征及血气指标的改善程度显著优于对照组(P<0.01)。结论应用NPPV可显著改善ACPE患者的症状、体征及血气分析结果,该方法可作为ACPE的一线治疗方案,值得推广。
Objective To explore the clinical therapeutic value of non-invasive positive pressure ventilation （NPPV） in the treatment of acute cardiogenic pulmonary edema （ACPE）.Methods A total of 65 patients with ACPE were randomly divided into control group （30 patients） given routine therapy and observation group （35 patients） added with NPPV therapy.The improvement time of dyspnea,pink frothy sputum and wet pulmonary rale in both groups were recorded while vital signs including respiratory rate （RR）,heart rate （HR） and blood pressure （BP）,and blood gas consisted of partial pressure of oxygen and carbon dioxide and oxyhemoglobin saturation before and after treatment were compared.Results Before treatment,there were no significant differences between 2 groups.However,observation group was evidently shorter in improvement time and more superior in vital signs and blood gas indexes than control group after treatment,and the differences were significant （P ＜ 0.01）.Conclusion The application of NPPV can obviously promote the symptoms,vital signs and blood has analysis results,which can be widely utilized in clinic as the first-line treatment for ACPE patients.
出处
《实用临床医药杂志》
CAS
2014年第11期37-39,共3页
Journal of Clinical Medicine in Practice
基金
中国高校医学期刊临床专项资金(11321312)
关键词
急性心源性肺水肿
无创正压通气
生命体征
血气分析
acute cardiogenic pulmonary edema
non-invasive positive pressure ventilation
vital sign
blood gas analysis
