无创双水平正压机械通气在急性心源性肺水肿中的应用被引量：11

Application of bilevel non-invasive ventilation in the treatment of acute cardiogenic pulmonary edema.

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摘要目的探讨无创双水平正压机械通气(BNIV)在急性心源性肺水肿(ACPO)中的疗效及其安全性。方法将52例ACPO患者随机分为常规组(27例),BNIV+药物治疗组(BNIV组)25例。观察两组患者病情缓解时间,即开始治疗后0.5、1、2h及3d后心功能分级指标以及住院期间的病死率等。结果BNIV组患者的心功能分级指数在开始治疗后0.5、1、2h及住院期间的病死率明显优于单纯药物治疗组(P<0.05);3d时心功能分级,两组无显著性差异(P>0.05);BNIV组的治疗成功率在0.5、1、2h明显优于常规组(P<0.05);而3d后的成功率在两组之间无显著性差异。结论BNIV在辅助药物治疗ACPO中可明显加快病情的改善,提高早期治疗成功率,降低住院期间的病死率。 Objective To study the safety and effect of bilevel non-invasive ventilation(BNIV) in the treatment of acute cardiogenic pulmonary edema(ACPO).Methods 52 ACPO cases were randomly divided into routine medication group(n=27) and BNIV+medication group(BNIV group,n=25).NYHA grades at 0.5 h,1 h,2 h and 3 days after treatment and hospitalization mortality rate were observed in both group.Results NYHA grades at 0.5 h,1 h and 2 h after treatment and the hospitalization mortality in BNIV+medication group were superior to medication group^(P<0.05) ;but no difference was found between two groups after 3 days(P>0.05).The success rate in BNIV+medication group at 0.5 h,1 h and 2 h was significantly superior to medication group(P<0.05) but no difference in success rate was found between two groups after 3 days.Conclusion ACPO treated by BNIV+medication can improve the disease,increase the early success rate and decrease the hospitalization mortality.

作者叶飞杨松陈绍良段宝祥张俊杰单守杰林松戴振林张丰富贾海波

机构地区南京医科大学附属南京第一医院心内科江苏省宜兴市人民医院心内科

出处《中国综合临床》北大核心 2005年第3期195-197,共3页 Clinical Medicine of China

关键词心源性肺水肿正压机械通气 Cardiogenic pulmonary edema Ventilation

分类号 R541.6 [医药卫生—心血管疾病]

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