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低分子肝素治疗骨转移癌患者下肢深静脉血栓的疗效观察 被引量：6

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摘要 目的探讨低分子肝素(LMWH)治疗骨转移癌患者下肢深静脉血栓(DVT)的疗效和安全性。方法对51例骨转移癌合并DVT患者应用低分子肝素钠治疗,对其治疗前后的临床症状、体征、血小板(Plt)、部分凝血活酶时间(APTT)、D-二聚体(D-Dimer)进行比较。结果骨转移癌合并DVT患者治疗后DVT的总有效率为90.2%;治疗前后D-Dimer差异有统计学意义(P<0.01)。用药期间9例(17.6%)患者发生出血倾向,但无严重并发症。结论LMWH治疗骨转移癌合并DVT疗效确切,安全性较高。
作者 齐典文 胡彤宇 张国川 扈文海 郭昶志 赵茗
机构地区 河北医科大学第三医院河北骨科生物力学重点实验室
出处 《山东医药》 CAS 2014年第25期61-62,共2页 Shandong Medical Journal
基金 河北省卫生厅资助项目(20130532)
关键词 骨骼肿瘤 低分子肝素 下肢深静脉血栓 治疗
分类号 R738.1 [医药卫生—肿瘤]
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参考文献14

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二级参考文献37

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山东医药
2014年 第25期

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