摘要
以 6wt %NaOH 4wt%尿素为纤维素的新溶剂 ,采用溶液共混法制备出纤维素 甲壳素共混膜 ,为甲壳素在碱性溶液中制膜提供了新的方法 .红外光谱、X 射线衍射、扫描电镜和力学性能、抗凝血性能测试结果表明 ,共混膜中甲壳素含量低于 4 0wt%时 ,纤维素与甲壳素分子间具有良好的相容性 ;在纤维素中引入适量甲壳素可提高共混膜的抗张强度 ,共混膜的干、湿态抗张强度在甲壳素含量 10wt%时最大 ,其值分别为 89 1MPa和 4 3 7MPa ,比纯态纤维素膜的干、湿态抗张强度分别提高了 6 7%和 11 5 % ;甲壳素的引入可明显降低血小板在共混膜表面的粘附、凝聚与变性 ,增大共混膜的抗凝血参数 ,甲壳素含量达到 5 0wt%时 。
The blend films based on cellulose and chitin were prepared by solution casting 6% (wt) NaOH/4 wt% urea as a new solvent system for cellulose which is a novel way to prepare the chitin film from the alkali solution. The structure and morphology of the blend films were investigated by infrared spectroscopy(IR) X-ray diffraction(X-RD) and scanning electron microscope (SEM), respectively. The interaction and properties in the blend films were further discussed. IR results suggested that the strong effect due to hydrogen bonding resulted in the changes of crystalline structure because of the addition of chitin, which was also confirmed by X-RD test. Such interaction directly affected the blend miscibility. When the content of chitin lower than 40 wt% the blend films exhibited a good miscibility at a molecular scale, and or else the microphase separation occurred. The tensile test showed that introduction of chitin with moderate content can effectively enhance the tensile strength (sigma(b)) of the blend films. Furthermore, the blend film containing the 10 wt% of chitin content exhibited 89.1 MPa of sigma(b,dry) and 43.7 MPa of sigma(b,wet) respectively, which were enhanced by 6.7% and 11.5% compared to that of the cellulose film. However, the increase of chitin content resulted in the decrease of water resistivity ( R) of the blend films, suggesting that the coarse structure due to the. microphase separated structure makes the water easily interpenetrate into the blend films. Simultaneously the introducing of chitin can effectively lower the adhesion, agglomeration and denaturalization of palate, namely enhance the blood anticoagulant index of the blend film. The results showed that the blend films with the chitin content higher than 50 wt% exhibited the best blood anticoagulant activity. This kind of blend film is promising in the field of medical materials.
出处
《高分子学报》
SCIE
CAS
CSCD
北大核心
2002年第4期525-529,共5页
Acta Polymerica Sinica
基金
国家自然科学基金资助项目 (基金号 2 99770 14 )
