期刊文献+

COX-2及其抑制剂与结直肠肿瘤 被引量:4

COX-2,COX-2 Inhibitor and Colorectal Tumors
暂未订购
导出
摘要 动物实验、细胞学研究、流行病学研究和临床资料皆证明COX 2抑制剂可以在早期阶段阻止结直肠癌的发生。就COX 2理化特征、表达与调控。 Animal models,cytological research,epidemiological studies and clinical trials suggest that COX 2 inhibitor may reduce the risk of colorectal tumors in early stage.Physic and chemical characters, expression and regulation of COX 2 and the relationship between COX 2 and colorectal tumors were reviewed in this article.
机构地区 山东省肿瘤医院
出处 《肿瘤防治杂志》 2002年第4期487-490,共4页 China Journal of Cancer Prevention and Treatment
关键词 COX-2 抑制剂 结直肠肿瘤 综述文献 COX 2 inhibitor colorectal tumor review literature
  • 相关文献

参考文献49

  • 1Heath CW Jr;Thun M J;Greenberg ER.Nonsteroidal anti-inflammatory drugs and human cancer. Report of an interdisciplinaryresearch workshop[J],1994(10).
  • 2Mamett LJ.Aspirin and related nonsteroidal anti-inflammatory drugsas chemopreventive agents against colon cancer[J],1995(02).
  • 3Vane JR.Inhibition of prostaglandin synthesis as a mechanism of action for the aspirin-like drugs,1971.
  • 4Smith WL;Meade EA;De Witt DL.Interactions of PGH synthaseisozymes-1 and-2 with NSAIDs[J],1994.
  • 5Appleby SB;Ristimaki A;Neilson.Structure of the human cyclooxygenase-2 gene,1994.
  • 6Morita 1;Schindler M;Regier MK.Different intracellular locations for prostaglandin endoperoxide H synthase-1 and-2,1995.
  • 7Robert A.Cytoprotection of the gastrointestinal mucosa,1983(28).
  • 8Whelton A.Nephrotoxicity of nonsteroidal anti-inflammatory drugs:physiologic foundations and clinical implications,1999(106).
  • 9Dewitt D;Smith WL.Yes but do they still get headaches?[J],1995(08).
  • 10Appleby SB;Ristimaki A;Neilson K.Structure of the humancyclo-oxygenase-2 gene,1994.

共引文献7

同被引文献66

引证文献4

二级引证文献18

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部