摘要
目的 探讨血清丙二醛 (MDA)、一氧化氮 (NO)在急性胰腺炎中变化及其临床意义。方法 32例急性胰腺炎 (其中 13例重型 ,19例轻型 )采用硫代巴比妥法测定血清MDA ,硝酸还原酶法测定血清NO ,并以 16例急性胆囊炎为对照。结果 血清MDA急性胰腺炎较急性胆囊炎明显升高 ,NO急性胰腺炎较急性胆囊炎明显下降 ,重型胰腺炎与轻型胰腺炎相比有明显差异 ,分别为 19.6 8± 16 .14 μmol/L、12 .82± 12 .78μmol/L、19.4 5± 15 .2 4 μmol/L、15 .92± 7.2 2 μmol/L。 结论 血清MDA、NO测定有助于预测急性胰腺炎的严重程度 。
Objective To investigate the changes and clinical significance of serum malondialdehyde (MDA)?nitric oxide (NO) in acute pancreatitis (AP) patients.Methods Serum MDA was measured by sulfobarbiturate and serum NO was measured by nitrate reductase in 32 cases of acute pancreatitis (13 severe acute pancreatitis,SAP;19 mild acute pancreatitis,MAP),16 cases of acute cholecystitis was takem as controls.Results Serum MDA in AP was significantly higher than that in acute cholecystitis,serum NO in AP was significantly lower than in acute cholecystitis.The serum MDA?NO between SAP and MAP were found significantly different (19.68±16.14μmol/L?12.82±12.78μmol/L?19.45±15.24μmol/L?15.92±7.22μmol/L,respectively, P <0.05).Conclusion The measurement of serum MDA?NO may contribute to predict the severity of AP,to guide clinical management.
出处
《苏州大学学报（医学版）》
CAS
2002年第4期428-429,共2页
Suzhou University Journal of Medical Science
