摘要
采用硝酸还原酶法，测定了肝硬化、腹腔感染和我国首例小肠移植成功患者血清一氧化氮和TNF。结果表明，肝硬化病人血清一氧化氮和TNF显著高于正常人（P＜0．01），但两者相关不显著；腹腔感染病人血清一氧化氮水平低于正常人（P＜0．01），并与24小时尿中尿素呈显著负相关，TNF水平高于正常人。我国首例小肠移植成功病人分别手术后多时期点测得血清一氧化氮和TNF在正常水平，表明无排斥现象发生，与同期肠粘膜活俭亦无排斥反应结论一致。
Using nitrate reductase methods, the serum levels of NO and TNF were measured in patient withintraabdominal sepsis, cirrhosis of the liver and the patient with successful small bowel transplantation. The results indicated that NO and TNF levels are higher in cirrhotic patients than in those healthy adults (P<0. 01), butNthere is no marked relevance ; NO level in septic patient is lower than that in healthy ones (P<0. 01), but it isNegatively relevant to the urea level in 24 hour urine, that TNF level is higher than normal. Normal NO and TNFlevels determined in various intervals in the patient after successful small bowel transplantation indicated that thereis no organic rejection, and it correlated well with cocomitant intestinal mucosa biopsy. The mechanism of variation and action of the NO in hepatic cirrhosis and abdominal sepsis were also discussed.
出处
《江苏医药》
CAS
CSCD
1997年第8期533-535,共3页
Jiangsu Medical Journal
关键词
腹部外科
一氧化氮
腹腔感染
小肠移植
肝硬变
Nitric oxide Hepatic cirrhosis Abdominal sepsis Small bowel transplantation
