摘要
目的:建立自乳化莪术油软胶囊中莪术油含量测定方法。方法:采用可见光分光光度法,将胶囊中内容物用无水乙醇稀释后,采用香草醛硫酸溶液显色,于(520±2)nm检测,测定其吸收度。结果:莪术醇浓度在40～320μg·ml^(-1)范围内,线性关系良好(r=0.9979),回收率96.59％,RSD为1.03％。结论:本方法准确,可靠,适合用于自乳化莪术油软胶囊制剂的含量测定。
OBJECTIVE: To study the determination method of self-emulsifying Curcuma oil soft capsule. METHODS: The content of soft capsules was diluted by anhydrous alcohol, and then colored by sulfuric acid-vanillin reagent. RESULTS: The absorbance was measured at ( 520±2 ) nm. Curcumenol revealed linearity over the arrange of 40 -320μg·ml-1, the average recovery was 96.59% ,and RSD was 1.03%. CONCLUSION: This method is accurate, reliable, and it is suitable for the content of determination of self-emulsifying curcuma oil soft capsules.
出处
《药学实践杂志》
CAS
2002年第4期240-242,共3页
Journal of Pharmaceutical Practice
