摘要
目的探讨原发性高血压中医分型与血浆内皮素 /血清一氧化氮的变化规律。方法10 2例原发性高血压患者按中医辨证分型为阴阳两虚型 (30例 )、痰湿壅盛型 (2 3例 )、阴虚阳亢型 (31例 )、肝火亢盛型 (18例 )和正常血压对照组 (2 3)例。分别检测血浆内皮素 (ET)、血清一氧化氮 (NO)浓度 ,并分析之间的关系。结果除肝火亢盛外 ,高血压中医各证型较正常对照组ET明显增高 ,NO明显降低。ET值 :阴阳两虚型 >痰湿壅盛型 >阴虚阳亢型 >肝火亢盛型。NO值 :阴阳两虚型 <痰湿壅盛型 <阴虚阳亢型 <肝火亢盛型。结论ET/NO可作为高血压中医证型严重度的判断指标。
Objective To investigate the chaning regularity between the TCM classification in essential hypertension and plasma endothelin, serum nitric oxide. Methods 102 patients with essential hypertension were divided into different types with TCM classification i.e., yin-yang deficiency type (30 cases), stagnation of phlegm-dampness type (23 cases),hyperactivity of yang due to yin deficiency type(31cases),liver-fire excess type (18cases),and a control group with normal blood pressure(23cases). The concentration of plasma ET and serum NO was tested respectively and their relationship was analyzed. Results In contrast with the control group with normal blood pressure, ET raised and NO declined obviously in types with TCM classification except in liver-fire excess type. ET value: yin-yang deficiency type >stagnation of phlegm-dampness type > hyperactivity of yang due to yin deficiency type >liver-fire excess type . NO value: yin-yang deficiency type< stagnation of phlegm-dampness type <hyperactivity of yang due to yin deficiency type < liver-fire excess type. Conclusion ET/NO can be used as the index for judging the order of severity hypertension with TCM classification.
出处
《贵州医药》
CAS
2002年第6期502-503,共2页
Guizhou Medical Journal
基金
贵州省教委资助项目
关键词
原发性高血压
中医分型
内皮素
一氧化氮
EH
Essential hypertension Traditional Chinese medical classification Endothelin Nitrix Oxide
