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Experimental study on interbody fusion with CFR/PEEK

Experimental study on interbody fusion with CFR/PEEK
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摘要 Objective:To studythebiocompatibilityof CFR/PEEKcompositeinbonetissueafterimplantedinlumbar intervertebralspaceandto evaluateitsroleintheinterbodyfusioncomparedwithallograftbone.Meth ods:Thirteen beagleswerechosenamongwhich7animalswereimplantedwiththedisk-likeCFR/PEEKcompositein thelumbar intervertebralspaceand6wereimplantedwithallograftbone.X-ray,QCTandhistologicalexaminationwereem-ployedat6,12,and24monthspostoperatively.Results:TheX-rayresultswereinconformitywiththatof QCT.His-tologicalexaminationshowedtheanteriorsofttissueof theimplantexhibiteda nonspecificforeignbodyreaction withconnectivetissuethebiomaterials.Carbonfragmentwereseeninthesurroundingtissueandsomeof thedebric werephagocytosedby foreignbodygiantcell.Histologicalexaminationof boneand materialshowednew bone growthalonetheholeof CFR/PEEKimplant.Con clu sion:CFR/PEEKhasexcellentbiocompatibilityto bonetissue. Objective:To studythebiocompatibilityof CFR/PEEKcompositeinbonetissueafterimplantedinlumbar intervertebralspaceandto evaluateitsroleintheinterbodyfusioncomparedwithallograftbone.Meth ods:Thirteen beagleswerechosenamongwhich7animalswereimplantedwiththedisk-likeCFR/PEEKcompositein thelumbar intervertebralspaceand6wereimplantedwithallograftbone.X-ray,QCTandhistologicalexaminationwereem-ployedat6,12,and24monthspostoperatively.Results:TheX-rayresultswereinconformitywiththatof QCT.His-tologicalexaminationshowedtheanteriorsofttissueof theimplantexhibiteda nonspecificforeignbodyreaction withconnectivetissuethebiomaterials.Carbonfragmentwereseeninthesurroundingtissueandsomeof thedebric werephagocytosedby foreignbodygiantcell.Histologicalexaminationof boneand materialshowednew bone growthalonetheholeof CFR/PEEKimplant.Con clu sion:CFR/PEEKhasexcellentbiocompatibilityto bonetissue.
作者 石志才 李家顺 贾连顺 袁文 侯铁胜 李明 朱晓东
出处 《Journal of Medical Colleges of PLA(China)》 CAS 2001年第2期111-114,共4页 中国人民解放军军医大学学报（英文版）
关键词 POLYETHERETHERKETONE COMPOSITE FUSION IMPLANT CFR PEEK 体内融合 骨移植物 生物适合性
分类号 R392.1 [医药卫生—免疫学]
  • 相关文献

参考文献8

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二级参考文献10

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Journal of Medical Colleges of PLA(China)
2001年 第2期

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