摘要
【目的】了解羊水板层小体计数在中晚期妊娠不同孕周的分布及其与胎肺成熟度的关系。【方法】对妊娠 17～42周的 2 0 4例孕妇进行羊水板层小体计数测定 ,其中 5 6例与羊水泡沫试验对照 ,分析羊水板层小体数与孕周、羊水泡沫试验及新生儿呼吸窘迫综合征的关系。【结果】羊水板层小体数与孕周及泡沫试验有明显的相关性 ,数值随着孕周的增加而增加 ,34周后增加明显。将羊水板层小体数与泡沫试验对照 ,根据ROC曲线 ,得出判断胎肺成熟度的界值为 38× 10 9/L ,大于 38×10 9/L表示胎肺成熟 ,其灵敏度 10 0 % ,特异度 93 8% ,阳性预测值 37 4% ,阴性预测值 10 0 %。新生儿发生呼吸窘迫综合征者测定值均 <38× 10 9/L。【结论】羊水板层小体数随着孕周增加而增加 ,其测定方法简单 ,快捷 ,客观 ,可作为预测胎肺成熟度的一个指标。
To determine the distribution of amniotic fluid lamellar body with various gestational age during middle and later trimester and to use this indicator to predict fetal lung maturity. Amniotic fluid lamellar body counts had been performed in 204 women with 17 42 gestational weeks and foam test had been performed in 56 gestational women among those patients. Lamellar body counts increased with gestational age and significantly increased after 34 weeks. It was correlated with the result of foam test. Compared with foam test, the lamellar body count cutoff value that predicted fetal lung maturity was 38×10 9/L. A maturity criterion of >38×10 9/L for lamellar body count yielded values for diagnostic sensitivity of 100%, specificity of 93 8%, positive predictive value of 37 4% and negative predictive value of 100%.[Conclusions] Amniotic fluid lamellar body count increases with the increasing gestational age. Advantages of this test include simplicity, objectivity, and universal availability of instrumentation, can be used as a predictor of fetal lung maturity.
出处
《中山医科大学学报》
CSCD
北大核心
2002年第4期277-279,共3页
Academic Journal of Sun Yat-sen University of Medical Sciences
关键词
胎儿器官成熟度
呼吸窘迫综合症
产前诊断
fetal organ maturity
respiratory distress syndrome
prenatal diagnosis
