摘要
【目的】研究产后 5d及 42d雌二醇、孕酮、催乳素变化与产后抑郁的关系。【方法】应用病例对照研究的方法 ,对 35例产后抑郁症患者 ,使用放射免疫方法测定分娩前后血清催乳素 (PRL)、孕酮 (P)及雌二醇 (E2 )水平的变化。【结果】抑郁组产后 5d ,42d血清PRL高于对照组 ,产后 5dP高于对照组 ,产前E2 抑郁症组高于对照组 ,产后 5d ,42d与产前E2 的差值 ,抑郁症组高于对照组 (P <0 0 5 )。【结论】在胎盘娩出后 ,雌二醇、孕酮及催乳素的改变与产后抑郁症的发生有关。
Objectives] To study the relationship of the changes of hormone in the patients with the postpartum depressive disorder on the 5th and 42nd days of postpartum. The blood samples of 35 women with postpartum depressive for serum prolactin(PRL), progesterone(P) and estradiol(E 2) level at antepartum and on the 5th, 42nd days after delivery were assayed with radioimmunoassay by case control study. The serum level of PRL on the 5th,42nd days after delivery, P on the 5th postpartum, E 2 in antepartum were showed higher in the depressed group compared with control group.There was a significant difference in the changes of the serum E 2 before and after delivery between the depressed group and control group(P<0 05). [Conclusions] There is a difference in the hormone changes in E 2, P and PRL level in the patients with postpartum depression after the expulsion of placenta.
出处
《中山医科大学学报》
CSCD
北大核心
2002年第4期274-276,共3页
Academic Journal of Sun Yat-sen University of Medical Sciences
关键词
产后抑郁症
血液
雌二醇
孕酮
催乳素
depression,postpartum/blood
estradiol
progesterone
prolactin
