摘要
目的 探讨纤维连接蛋白(FN)在多器官功能不全综合征(MODS)中的表达规律及其意义。方法 应用免疫组化技术,对20例MODS和12例非MODS死亡标本的心、肺、肾组织的FN进行检测。结果 非MODS的心、肺、肾组织FN表达多为阳性或强阳性,MODS多为弱阳性或阳性;两组间比较,差异显著(P<0.01)。结论 MODS时组织中FN降低,FN降低可能导致MODS。
Objective To study the relationship between the expression of FN in heart, lung and kidney and the mechanism of multiple organ dysfunction syndrome (MODS). Method The Fn in heart, lung and kidney in 20 autopsy cases of MODS were studied immunohistochemically by using anti-FN as the first antibodies. Results The expression of FN in the MODS group were significantly decreased as compared with the control group (P<0.01). Conclusion The expression of FN decreased in MODS. It might be one of the mechanism of MODS.
出处
《中国法医学杂志》
CSCD
2002年第3期131-133,共3页
Chinese Journal of Forensic Medicine
基金
卫生部基金资助
基金编号94-1-101。
