摘要
目的 :探讨血浆内毒素(ET)、肿瘤坏死因子(TNF α)在酒精性脂肪肝发病机制中的作用。方法 :对20例酒精性脂肪肝以及对照组测定其血清酶(ALT、AST、GGT)与血浆ET、TNF α ,并对观察组血清酶与血浆ET、TNF α作动态观察及相关分析。结果 :观察组血浆ET、TNF α与对照组存在显著性差异(P<0 05) ,观察组血清酶(ALT、AST、GGT)与血浆ET成正相关(r分别为0 434、0 586和0 734) ,与TNF α也成正相关(r分别为0 746、0 638、0 874)。结论 :酒精性脂肪肝的发生、发展与血浆ET、TNF
Objective:Explore the functions of plasma ET and TNF α on the invasion mechanism of alcoholic fatty liver(AFL).Methods:Test the ALT,AST,GGT and plasma ET,TNF α of 30 cases of AFL and control group,and make dynamic observation and relative analysis to ALT and plasma ET,TNF α of the observatin group.Results:The plasma ET,TNF α of the observation group had marked difference with that of the control group(P<0 05);in the observation group,the ALT,AST and GGT had positive correlation with plasma ET(r=0 434,0 586,0 734 respectively) and TNF α(r=0 746,0 638,0 874 respectively).Conclusion:The occurrence and development of AFL were closely related with plasma ET and TNF α.
出处
《浙江中医学院学报》
2002年第3期26-27,共2页
Journal of Zhejiang College of Traditional Chinese Medicine
